Reference no: EM133918046
Case Study: DIABETES AND INSULIN SIGNALING
Part one:
1. List the four parts of a signaling pathway.
2. What is the difference between an ionotropic and metabotropic pathway?
3. What is/are metabolism/metabolic processes?
4. How do signaling pathways affect metabolic processes of cells?
5. What is the enzymatic activity of a kinase and a phosphatase?
6. Why are only small amounts of insulin required to regulate glucose uptake by cells?
7. Why would a signaling pathway need to be regulated?
Part two:
8. How does insulin act as a signal molecule?
9. Does insulin act on an ionotropic or a metabotropic receptors?
10. What types of cells have insulin receptors?
11. How does the lack of insulin affect the ability of insulin sensitive cells to use glucose?
12. Describe how insulin acts on GLUT transporters in muscle cells.
13. What happens to the glucose after it enters muscle cells?
14. Describe how insulin acts on GLUT transporters in liver cells.
15. What happens to glucose after it enters liver cells?