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A mutation that is due to a dominant allele causes guinea pigs to lose their body hair. A breeder is trying to establish a colony of mutant "hairless" guinea pigs to sell to pet stores. He has a male mutant guinea pig that he wants to use for the breeding. However, due to an error in record keeping, he is uncertain of the mutant male's genotype. He decides to mate a true-breeding normal guinea pig with the mutant male and notices that 100% of the offspring (F1 generation) have the hairless mutant phenotype.
The cross that was conducted is often used by breeders to determine the genotype of an individual that shows the dominant trait. What is the name of this specific cross?
The hairless mutation is dominant and it occurs because there was a deletion of the 3 bases that are bolded in the coding sequence of the gene - 5' CATTGGTA 3'. The deletion or removal of the bases is a mistake or error that occurs during which phase of the cell cycle?
The mutation in the above coding sequence causes the protein that is responsible for hair follicle stimulation in guinea pigs to be non-functional. This protein is made and secreted by skin or epidermal cells. What organelle would produce this protein?
Genetic variation in the population of organisms is good; but, sometimes mutations can be harmful or cause genetic disorders.
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