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Spherocytosis is an inherited blood disease in which the erythrocytes (red blood cells) are spherical instead of biconcave. This condition is inherited in a dominant fashion, with SPH (the mutant allele) dominant to SPH . In people with spherocytosis, the spleen "reads" the spherical red blood cells as defective and removes them from the bloodstream, leading to anemia. The spleen in different people removes the spherical erythrocytes with different efficiencies. Some people with spherical erythrocytes suffer severe anemia and some mild anemia, yet others have spleens that function so poorly there are no symptoms of anemia at all. When 2400 people with the genotype SPH SPH were examined, it was found that 2250 had anemia of varying severity, but 150 had no symptoms. a) Does this description of people with spherocytosis represent incomplete penetrance, variable expressivity, or both? Explain your answer. b) Can you derive any values from the numerical data to measure penetrance or expressivity?
In ecology, body size is an important variable. Which of the following implications of body size is truANIMALe?
Determine how many chromosomes will be present in the somatic nuclei of individuals
What were the contributions of Nestorian Christians, Muslims, and Jews to Medieval Science?
You are studying the cleavage of two substrates by chymotrypsin,an ester and an amide. Except for the scissile bond, the substratesare identical. With which substrate will the acyl enzyme be formedmore rapidly? Why?
Name the two organelles (one in animal cells and one in plant cells) that have their own DNA that are NOT located in the nucleus.
If the epidermis is wounded (cut), epithelial cells must migrate out on the ECM of the dermis to cover the wounded area. Epithelial cells migrate through the use of transient focal adhesions.
The following statement(s) is true about eukaryotic insulators.
Suppose if the average hydrostatic pressure in glomerular capillaries is 55 mmHg, the hydrostatic pressure in Bowman's space is fifteen mmHg, the average colloid osmotic pressure in the glomerular.
A 22-year-old Honduran woman presents to an urgent care center complaining of a rash and joint pains in the wrists and knees for 2 days. Her rash was preceded by 3 days with a fever, malaise, headache, mild conjunctivitis, mild cough, and lymphade..
Explain why is RNAse added to PCR? Prevent RNA from annealing to the template strand. But what else is it used for
The cerebral cortex is highly folded. Why might this be an advantage for the functions of the cerebrum?
what type of channel is in a presynaptic membrane in a presynaptic cell? A. ligand gated B. voltage gated Na+, K+ C. voltage gated Na+, K+, Ca2+.
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