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Pompe's disease is one of a class of lysosomal storage diseases in which one or more enzymes that are normally found in the lysosomes are defective or absent. In Pompe's disease, the enzyme that normally breaks down glycogen is absent.
Describe what you would see in an electron micrograph of a liver cell from an individual with Pompe's disease. What are some possible consequences of having such a disease? Can you think of an effective way to treat it?
Determine the genotypes of the parents, F1 offspring and F2 offspring and the probable mode of inheritance? Check your answer with the appropriate statistical test.
One way methane is produced is via reduction of carbon dioxide, which serves as electron acceptor, with molecular hydrogen, which serves as electron donor.
A prison guard states that an inmate threw and unknown liquid on him. This is a felony charge of harassment. In order for this charge to be prosecuted, you must show a bodily fluid was thrown on the guard.
Phenylketonuria is extremely common in Ireland, affecting approximately 1 in 4500 live births. Determine the frequency of PKU carriers?
What is the pK of the weak acid HA if a solution containing 0.1M HA and 0.2M A has a pH of 6.5?
Determine the significance of the observation that knocking out MyD88 abrogates increases in Factor B and C3a but knocking out of TRIF does not ? Describe in molecular terms.
A patient suffers with symptoms of an upper respiratory infection, especially nasal congestion. Determine which category of autonomic drugs would be the best choice for his treatment?
You have three tubes containing solutions of the protein human chorionic gonadotrophin (HcG) in PBS. All three contain 2 ml. Tube A is at a concentration of 28 mg/ml. Tube B is at a concentration of 78 mg/ml. Tube C is at a concentration of 40 mg/..
Peter Mitchell and colleagues determined that the total proton motive force across the inner mitochondrial membrane at 37 degree celsius was 230mV, of which 70% was due to the electrical potential. What was the pH gradient across the membrane?
The formation of methylmercaptan from ingested asparagus is a recessive trait. To find out if you are a methylmercaptan forming individual, simply eat a serving of asparagus and wait approximately 20 minutes before urinating.
Are temperature gradients present in all biomes? What is one example of an adaptation to a colder temperature range?
Eukaryotic genes differ than prokaryotic genes. Please define, in depth, the post-transcriptional modification that a eukaryotic mRNA goes through before it leaves the nucleus and how this differs from the transcriptional events in a prokaryotic s..
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