Describe what will occur during your experiment

Assignment Help Other Subject

Reference no: EM131742361

Homework set: Physiology

Nervous System

1. What effect would each of the following have on synaptic transmission? (Synaptic transmission is when neurotransmitters from on neuron bind and activate a second neuron.)
a) you administer a drug which inactivates acetylcholinesterase

b) you cut the axon of the postsynaptic cell

c) you administer a drug which binds to the norepinephrine receptor but doesn't cause the activation of the associated G-protein

2. You are testing the effects of drugs on three identical, isolated neurons. You know that if no drug is applied, the neuron (under the appropriate conditions) is capable of EPSP formation, action potential production, and acetylcholine release. What effect would each of the following three drugs have on these three functions?

a) Drug #1 blocks voltage-gated calcium channels

b) Drug #2 blocks voltage-gated sodium channels

c) Drug #3 causes chemically gated sodium channels to open and remain open indefinitely

3. You have four identical Isolated neurons which are capable of forming excitatory ACh synapses on both ends. You treat each of these neurons with a different drug. You then apply acetylcholine to the dendrites of each neuron, and test to see if that neuron is capable of EPSP formation, action potential production, and/or acetylcholine release. The results to your studies are given here:

Neuron	EPSPs?	APs?	ACh released?
#1 (Drug A)	yes	yes	no
#2 (Drug B)	no	no	no
#3 (Drug C)	yes	no	no
#4 (Drug D)	yes	yes	yes

a) Which drug is probably a placebo? Explain.

b) Give a plausible explanation what each of the three other drugs might do, giving cellular and/or chemical details,

4. You have an impermeable membrane bag (i.e. nothing gets through its walls). You insert ACh receptors into the wall of this bag. The ACh receptors are from a synapse that forms IPSPs. Inside this bag there is 3% Na+, 4% K+ and 2% Ca2+. At time=0 sec you place the bag into a beaker of pure water. At time=30 sec, you add acetylcholine to the beaker. At time=60 sec, you add acetylcholinesterase the beaker.

a) Describe what will occur during your experiment.

b) Draw graph showing what happens to the concentration of each ion in the bag from 0 sec to 90 sec,

c) What will happen to the membrane potential of the bag during this experiment?

Muscular System

1. What effect would each of the following drugs have on shortening of the sarcomeres of skeletal muscles?
(a) drug blocks calcium release from terminal cistemae

(b) drug blocks calcium binding sites on troponin

(d) drug blocks myosin head binding sites on actin

(e) drug destroys tropomyosin

(t) drug inactivates acetylcholinesterase

(g) drug blocks acetylcholine receptors

(h) drug destroys troponin

2. What would happen if you administered a drug which completely blocked the norepinephrine receptors of the heart's SA node?

3. Draw 2 complete cycles of an ECG trace that corresponds to a person with a cardiac rate of 120 bpm. Label all waves and axes, and indicate what electrical event each wave (or complex) represents.

4. How far apart (in time) are the R waves on the ECG of a person whose heart rate is 100 bpm?

5. A person's heart rate is 105 bpm. Do they have tachycardia?

Reference no: EM131742361

Questions Cloud

What should a profit maximizing monopolist do : What should a profit maximizing monopolist do if she is currently producing where MC

Probability that the next card will be black than red : Red cards. You shuffle a deck of cards and then start turning them over one at a time. The first one is red. So is the second.

Probability of getting no fruit symbols : Slot machine. A slot machine has three wheels that spin independently. Each has 10 equally likely symbols: 4 bars, 3 lemons, 2 cherries, and a bell.

Good ability-to-job fit improves employee motivation on job : Hiring for a good ability-to-job fit improves employee motivation on the job. Companies may pick and choose who they want to drug test.

Describe what will occur during your experiment : Describe what will occur during your experiment - Draw graph showing what happens to the concentration of each ion in the bag from 0 sec to 90 sec

Importance of financial ratios and financial analysis : Discuss the purpose and importance of financial ratios and financial analysis. What are the limitations of financial ratio analysis?

Companies may pick and choose who they want to drug test : Genetic testing may be used as a basis for making employment decisions. Companies may pick and choose who they want to drug test.

Review problem related to champion bowler : Champion bowler. A certain bowler can bowl a strike 70% of the time. What is the probability that she goes three consecutive frames without a strike?

What is its sustainable growth rate : It has a total debt of 48,000 in total equity of 60,000. Last year it paid dividends of 6000. What is its sustainable growth rate?

User Account

All Pages