Reference no: EM133984528

Questions:

1. Describe the experiments done by the following scientists: a) Griffith, b) Avery, MacLeod, and McCarty, c) Hershey and Chase, and explain the results and conclusions for each of these experiments
2. Describe the three components of a nucleotide, how nucleotides are linked together to form a nucleic acid, which end of a DNA strand (5' or 3') new nucleotides are added onto, and define antiparallel
3. Describe how DNA is packaged and define histone and nucleosome
4. Describe the Meselson and Stahl experiment and define semi-conservative replication
5. Describe the roles of Rosalind Franklin, Francis Crick and James Watson in determining the structure of DNA
6. Explain how DNA is replicated in prokaryotes and the roles of DNA polymerase, RNA primers, RNA primase and DNA ligase
7. Define origin of replication, leading and lagging strand, Okazaki fragments and describe how the two new daughter strands of DNA are synthesized at a replication fork.
8. Describe how DNA is replicated in eukaryotes
9. Describe the location and function of telomeres, what happens at the telomeres each time a cell divides, and why most cells can only undergo about 50 cell divisions
10. Describe the function of telomerase, and describe the types of cells in which telomerase is active
11. Describe the proofreading function of DNA polymerase and define mismatch repair and excision repair
12. Define mutagen & give examples of naturally occurring and chemical mutagens and their effects on DNA