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A. Why is homologous recombination between nonsister chromatids preferred?
B.Is it possible to tell whether a DNA gap was generated during a homologous recombination eent that occurs at a heterozygous locus? Why or why not?
C. Based on its structure, explain how the synaptonemal complex could actually represent an obstacle to recombination.
D. Why is it important that resolvases function as symmetrical molecules with two active sites?
E. Explain why either a single- or double-strand break can result in a change in supercoiling.
F. The Cre/lox system is used to extensively to create "conditional knockouts" in mice, for example to delete a gene of interest in a particular tissue type. Describe how such a system might work.
Medical history elicits the facts that she lost her husband six months previously, has been extremely depressed, and is taking sleeping pills and not eating properly. What would doctor hypothesize about the probability of senile dementia in this case..
The thalamus is a brain structure that constantly recieves incoming visual, auditory, olfactory, tactile, thermal, and nociceptive sensory data at any given instant.
Phenylketonuria is a severe form of mental retardation caused by a recessive allele. The situation affects about 1 in 25,000 newborn babies.
An organism has a diploid chromosome number of 12. How many chromatids will be visible during metaphase of mitosis? How many chromosomes will be visible at the end of anaphase in mitosis? For the similar organism, how many chromosomes will be present..
Steve is in the midst of his Microbe experiment. He is increasing mold on a piece of peach. After five days in the baggie, the mold covers 88 square millimeters of the peach surface.
Assume you have a population of 3,320 AA; 640 Aa; and 12 aa genotype. Calculate the relative fitness w, and the selection coefficient for each 3 genotypes
How would you interpret this result? How might such a phage replicate its DNA.make sense in terms of Chargaff's rules.
Select a specific gene and a specific alteration. Explain the effects of the modifications and why it might contribute to the cancer.
Four proteins, each having a single polypeptide, are separated by SDS-PAGE: human cytochrome c , human serum albumin, bovine myoglobin.
Surface areas are important in biology because it constrain rates of transfer of light, heat, water, gases, food, forces, etc. Discuss and contrast the location, orientation and size of two surface areas.
While you measure the genotype frequencies of the population you get the following data. What will the frequency of Aa be in the next generation.
What measures would you suggest in the plan to actually reduce health risks? How would the plan allow the public to recognize pathogens are related to cause of diseases and other health problems?
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