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1. Regarding control of gene expression in eukaryotes, what effect does the binding of transcription factors to upstream promoter elements (or "modules") and elements/modules in enhancers have on the efficiency of assembly of the basal transcription factors to the core promoter?
2. Mutations that convert proto-oncogenes such as ras to active oncogenes are dominant, but those that knock out tumor supressor genes are recessive. Assuming mutations are equally likely in oncogenes and tumor supressor genes, why does oncogene activation happen more easily than suppressor gene inactivation?
A new enzyme you are studying has a Km of 7.0mM and a kcat of 126 per second. What will be the initial rate of reaction in units mM/min when 9.3 nanometer enzyme is reacted with 2.7 mM substrate. Report your answer in units if mM/min to nearest 1m..
Explore the role of the epigenome and/or other gene expression regulatory mechanisms in the development of cancer. Discuss in detail one possible epigenetic/post-transcriptional/post-translational target for cancer treatment, and identify the succes..
Suppose that the field of view is at 400x total magnification is 0.26mm. Determine the height of onion cells pictured below from and image observed at 400x.
Fossil with .9983 (Ur:Pb) in Africa
Describe the structure of atp and gtp. Describe how atp is produced during chemiosmosis. Illustrate two specific cellular processes that require atp and explain how atp is used in each process.
In a cross between a purple flowered plant and a white flowered plant, all 73 of the offspring had purple flowers. What are the most probable genotypes of the parent plants.
Think about the fructose-1,6-bisphosphatase reaction. Calculate the free energy change if the ratio of the concentrations of the products to the concentrations of the reactants is 24.1,
Explain why proteins are superior to both RNA and DNA for structural and enzymatic function?
An analyzer is studying a gene that codes for a very small polypeptide phe his gly cys gly. He treated the cells with different mutagens with the results to the protein.
The small intestine is specialized for absorption by the huge number of villi that line the intestinal wall. Villi have cells that generate intestinal enzymes which complete the digestion of peptides and sugars.
Explain the body's mechanisms for controlling blood glucose levels under normal and stress conditions.
Demonstrate that the overall process is equivalent to an isothermal expansion of the gas at T from V to 3V, where V is the original volume and Derive an express for dS for the overall process.
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