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A male volunteer named Conan was passively sensitized with IgE specific for Der f 1 (a potent house dust mite antigen/allergen). After an intradermal challenge with Der f 1, Conan displayed a typical skin lesion due to an immediate hypersensitivity reaction. Assess as either factually correct (= "true") or incorrect (= "false") the hypothetical results (11-20) obtained if the injection with sensitizing IgE was first preceded by an injection (at the same site) of Fc fragments of human IgE and then followed by the intradermal injection of allergen (Der f 1):11. The reaction would be exacerbated due to the increased local concentration of IgE Fc fragments.12. The reaction would be exacerbated due to the activation of complement.13. The reaction would be exacerbated due to the augmented release of cytokines.14. The reaction would be exacerbated due to the activation of macrophages and dendritic cells. 15. The reaction would be exacerbated, because the Fc fragments would activate NK cells.16. The reaction would be exacerbated, because the Fc fragments would activate mast cells and/or basophils.17. No reaction would occur because the Fc fragments would interact with the allergen and prevent it from gaining access to the sensitized mast cells.18. No reaction would occur because the Fc fragments would interact with the IgE antibodies making their antigen-binding sites unavailable for binding to antigen.19. No reaction would occur because the Fc fragments would interact with Fc? receptors on mast cells.20. Conan would develop anaphylaxis.
Organize the genotype in the table, define the origin (parental, single cross-over progeny and double-crossover progeny) and find out the order of the genes on the chromosome.
In Drosophila, the map directions of genes are given in map units numbering from one end of a chromosome to the other. The X chromosome of Drosophila is 66 m.u. long.
Which of the following movements is an example of extension? bending forward at the waist, kneeling, raising your arm laterally.
Determine what is it called when individual benefit is maximized by exploiting a resource to ruination?
Both RT and PR represent potential targets for antiretroviral drugs. Drugs called nucleoside analogs (NA) act against RT, whereas drugs known as protease inhibitors (PI) act against PR.
Mrs. Mulligan goes to her dentist and, after having a couple of cavities filled, her dentist strongly suggests that she reduce her intake of sodas and increase her intake of calcium phosphates in the foods she eats. Why give appropriate reasons.
Once you arrive at the distal ileum, go through mucosal membrane and enter the bloodstream via the Superior Mesenteric Vein. Evaluate the cellular organelles and other structures to the parts of a city. For instance, the nucleus is city hall and the ..
Explain how black and white pattern on the male siamese cat arises. If the oceans warm a few degrees, what impacts can you see on the landmasses, biologic community, and human populations? Are these positive or negative changes? Why with reason.
Explain why only certain cell types are permissive for transcription of HIV proviral DNA. What cellular factors are involved and why?
The 1st gene is responsible for determining blood group A,B or O. For this gene both A and B are dominant and O is recessive.
A 2-amino-purine can be incorporated into DNA in place of adenine. It can pair equally well with thymine or cytosine. What type of mutation do you expect it to cause.
The "Primordial soup" includes the mixture of elements and gases which are thought to have started life on the Earth. Specify where did the gases and elements come from?
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