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1. Using temozolomide as a first new alkalating agent approved for treatment of malignant gliomas describe its mechanism of action, clinical benefits and major site effects. Compare to other compounds with similar mechanism of action.
2. Present the comparison of clinical benefits of the use of antineoplastic drugs. What criteria are used for selection and for monitoring of most commonly used antineoplastic drugs?
3. Briefly present the mechanism of action of inhibitors of intracellular signaling used for antineoplastic therapy?
4. Give your insights regarding present and future of biological therapies for cancer treatment.
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Assume you perform a cross with the pea plant in question one and a pea plant with the genotype aabbccdd. What is the probability that an offspring will be aaBbccDd?
Five Hfr stains A through E are derived from a single F+ strain of E. coli. The following chart shows the entry time of the first five markers into an F- strain
Which planes when passed through the body would result in two sections, with each section containing a piece of the heart and a piece of each lung?
q. the peppered moth provides a well-known example of natural selection. the light-coloured form of the moth was
what is an example of a limiting factor that humans use to control the carrying capacity of an environment for a
Cells must control gene expression so that. In bacteria, a group of genes that code for functionally relatedenzymes, their promoter site, and the operator that controls themall function together as a
Scientific Inquiry, Controlled Experiments Then and Now Start by observing the living species around you. Ever wonder why a pollinator is attracted to a particular flower
q1. if there are 4000 children born to this generation how many will be expected to have ab blood under the conditions
1 what are the risk factors for developing diabetes?2 what other systems of the body are involved if applicable?3 what
Review the genetics of self-pollinated species and understand the breeding methods commonly used for self-pollinated crops.
How many times would you expect a restriction enzyme that recognizes a 6 base palindrome to cut a 16500 base piece of of DNA?
Based on your knowledge of the role of renal tubule in regulating ion balance, explain how a diuretic could induce hyperkalemia. Then explain how a different diuretic might induce hypokalemia.
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