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Question: Describe three factors that lead to negative resting membrane potential in an axon and cell body fo a neuron.Question: Discuss how would an increased number of Na+ leak channels in the membranes affect the sign and magnitude of the RMP? Justify your answer.
If a transferrin receptor has a cross-sectional area of 50 Angstroms X 100 angstroms (5x10nm), and how many receptors could be accomodated in a 100nm clathrin-coated vesicle assume that only 50% of surface area can be occupied by proteins.
Suppose an uncorrected missense mutation occurs in a zygote at the one-cell stage. The cell divides twice to make a four-cell embryo.
Choose one germline mutation as your topic focus. Discuss the normal function of the gene as well as the role of the mutated gene in cancer development and/or progression and discuss the nature of the virus, the type of cancers.
Determine how much in mL of .5 M NaOH total can you add to the solution in question 4 and still have a good buffer also Extimate the pH of a 0.05 M solution of TRIS acid (pKa=8.3)?
Why does some scientist think that areas protected from the otmosphere might have favoured the production of organic compounds on early earth.
The CAP activator protein and the Lac repressor both control the Lac operon. You construct cells that are mutant in the gene coding for the Lac repressor.
Assume you wish to conduct a chi-square test on a set of data obtained from a test cross, to determine whether two genes (A and B) are linked.
Yeast grows as a haploid cell. In the wild type cells in presence of O2, the pH of mitochondrial matrix is 8, however in cells along with this mutant S gene, the pH is 7. Explain all these results.
As a 1st step towards cloning the ding-dong gene from Drosophila, you find a transposon insertion within the gene.
A zoologist is investigating a population of squirrels whose coat color is controlled by a single gene whose two alleles (B 1 & B 2 ) are codominant.
Explain why are carcinomas more common than sarcomas? Describe your favourite new term or concept from this class in brief.
Critically illustrate out the cause, source and extent of diarrhetic shellfish poisoning, including an opinion on its occurrence and management in Canada and the USA.
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