Calculate the allelic and genotypic frequencies

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Hurler syndrome is an autosomal recessive disease caused by a deficiency of the enzyme alpha-L-iduronidase. Affected individuals are mentally retarded, have skeletal abnormalities, and short stature. The population incidence is about 1 in 90,000. Calculate the allelic and genotypic frequencies for the disease assuming Hardy-Weinberg equilibrium.

Reference no: EM1394003

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