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Mouse L-cells have proven to be an extremely useful model system for investigating the properties of cadherins because they do not normally express any cadherins. If different population of L-cells are transfected with vectors expressing one or the other of two different cadherins, and are the dissociated and mixed together, they segregate into two separate balls of cells, each held together by a different cadherin. If two populations of cells expressing different levels of the same cadherin are mixed, they segregate into a single ball of cells, with the low-expressing population on the outside.
A. Why do you suppose populations of cells expressing different levels of the same cadherin segregate with this characteristic layered structure? Why don't they segregate into two separate balls? Or a ball with the low-expressing population on the inside?
B. What sort of final architecture might you expect if you were to mix together two populations of cells that expressed P-cadherin in common, but, in addition, one population expressed E-cadherin and the other expressed N-cadherin??
Why are algae important in nature. Joan and Alex Smith have five daughters who are quite dissimilar in appearance and talents. Examine why this occurs based on the 2 events in meiosis that enhance genetic diversity.
Voltage dependent channels open through opening a gate that is a voltage sensor. Determine the names of these gates required for opening Na and K channels?
The median cubital vein typicall used for access to the venous system is a superficial vein that communicates between which vessels?
Blue skin color in smurfs is controlled by two independent biochemical pathways. Pathway one has two enzymatic steps under the control of gene A and gene B respectively
A major evolutionary trend among plants is: A reduction in size of the gametophyte and an increase in size of the sporophyte. A reduction in size of the sporophyte and an increase in size of gametophyte.
Describe the b cell response or humoral circulating immunity. Include the activation of b cell,clonal expansion, antibody production, b plasma and memory cells.
Disease and treatment associated with the neurotransmitter imbalance. Describe the significance of the dopamine neurotransmitter in our body.
Recognize factors that may affect the identification of an infectious agent form a patient. Also compare the types of tests performed on microbial isolates versus those performed on patients themselves in the process of microbial identification.
1. The duck-billed platypus and other monotremes differ from other mammals in that they? a. are aquatic. b. have mammary glands. c. lay eggs. d. have hair.
Do you think that using recombinant DNA technologies to change the genetic composition of human egg cell is ever justified? If so, what restrictions have to be placed on such a use.
Fruit files have three pairs of autosomes chromosomes with autosomal genes. For an autosomal gene, what is the maximum number of alleles an individual fruit fly can have?
List 3 benefits of microorganisms and 3 good things that will happen if we eliminated all microorganisms from the Earth.
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