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Aggravated by movement or weight bearing

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A 55 year old man presents with bone pain aggravated by movement or weight bearing. Physical exam is remarkable for pale conjunctivae. Lab results show a normocytic anemia and increased serum globulin level. Peripheral blood smear is significant for rouleaux formation and elevated monoclonal immunoglobulins. Urinary analysis reports + Bence-Jones proteins. Osteolytic bone lesions are seen on radiographs of the pelvis. This presentation is highly suspicious for which of the following?

A. paraneoplastic syndrome

B. Multiple Myeloma

C. metastatic bone disease

D. Paget's disease

Reference no: EM131865395

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