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You have just read a paper that the addition of caffeine to cells disrupts the DNA damage checkpoint and you would like to understand why. By searching for proteins that bind to caffeine, you isolate a protein, Caf1. You believe that Caf1 is involved in the DNA damage checkpoint because when you delete Caf1 from yeast cells and add a drug that causes DNA damage, the cells fail to arrest in the cell cycle. You give your Caf1 deleted cells to an undergraduate in the laboratory and ask him to take care of the strain for you while you take the weekend off to celebrate your finding. Upon your return, you find the poor undergraduate in tears. He explains that he thinks that he messed up the Caf1mutant strain while you were gone because after growing Caf1 and wild type cells in rich media and examining them during mitosis, Caf1 mutants looked the same as wild type cells. Are you concerned about the undergraduate student's findings? Why?
Describe the kind of feedback system involved in the heating system in your body using these key phrases: regulators, monitors and the coordination centre.
Under anaerobic conditions (a lack of oxygen), the conversion of pyruvate to acetyl CoA stops. Which of these statements is the correct explanation for this observation?
How does fatty acid concentration increase in the blood result in the activation of fatty acid oxidation in skeletal myocytes?
If these three genes were all assorting independently, how many genotypic and phenotypic classes would result in the offspring, and in what proportion, suppose simple dominance and recessiveness in each gene pair?
If a patient only has neutrophils and macrophages, what would be absent from the immune response?
The median cubital vein typicall used for access to the venous system is a superficial vein that communicates between which vessels?
The condition known as Bell's Palsy may result in drooping of the face. Typically, the condition is unilateral but in rare instances can be bilateral.
Explain the challenges and advantages of having internal gills over external gills for gas exchange and explain how increased stress levels can affect hormones which ultimately inhibit the immune system? Include all relevant glands and hormones in ..
Mobile pieces of DNA - transposable elements - that insert themselves into chromosomes and accumulate during evolution make up more than 40% of the human genome. Element of four types - long interspersed elements (LINEs), short interspersed elemen..
What is the function of the retina? What is the function of the choroid layer?
A researcher times rats in running a maze and finds that the average time for all of the rats to complete the maze is 34 seconds. She then breeds only those rats that ran the maze in 25 seconds or less and finds that the rats in generation two com..
What is special about ATP? How does a cell release energy from ATP? Please provide a specific explanation. Provide a non-biological analogy to describe the process.
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