Adaptive and directed evolution

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Question

"Adaptive and Directed Evolution" is an approach frequently used to improve microbial strains to a particular environment or to an industrial process in order to maximize bio-products or biomass formation. Describe:

1. What are the advantages and disadvantages compared to other improvement techniques?

2. How would you use this technique to improve ethanol tolerance in a microbial strain to be used in biofuel production? (include continuous vs. fed-batch approach, stressor type, expected number of generations before to observe the arise of adapted mutants, discuss approaches to screen mutants,etc).

Reference no: EM133932309

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