Active ingredient in intestine-solvent capsule

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Reference no: EM133915138

Question

MedZ contains 200 mg of the active ingredient in an intestine-solvent capsule. The active ingredient is effectively transported across the intestinal mucosa, which ensures that 78% of the drug is absorbed and enters the portal circulation. The drug undergoes a significant degree of first-pass metabolism, in which process 55% of the drug passing through the liver gets metabolized and therefore degraded to an inactive product. Calculate MedZ's bioavailability and show your calculations.

Reference no: EM133915138

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Active ingredient in intestine-solvent capsule : MedZ contains 200 mg of the active ingredient in an intestine-solvent capsule

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