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This study was done on 62 normal adults that were recruited through newspaper advertisement and notices on boards in the community. It was done using adults who had low to moderate daily caffeine consumption, on an average of 235 milligrams a day, or the equivalent I'm about 2 cups of coffee. This is a double-blind study, which is basically that the researcher nor this subject knew who was receiving caffeine and if so in what quantities. More than 50% of the participants who did not receive caffeine experienced moderate to severe headaches, about 10% had symptoms associated with anxiety and depression, and another 10% had significantly high readings of fatigue. Nearly 15% had symptoms associated with aches and pains.
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