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A question regarding the Jameison/Paladae experiment over the secretory pathway in a cell.
They exposed pancreatic cells to a pulse of radioactive methionine and then used EM autoradiography to track the movement of secreted proteins through the cell, from the beginning of translation until they reached their destination. Data curves shows that protein levels do not drop 0% in ER or Golgi, and the curve regarding secretory vesicles will not reach 100%, even if we wait a long time. Why is this? Select all that are correct. Not all membrane proteins are secreted after synthesis; some remain as resident proteins of other organelles. The half-life of the radioactive sulfur is pretty short, some of it has already decayed by 120'. Some secreted, radioactive proteins have been taken back up by the cell, through endocytosis. There is reverse traffic of proteins between organelle type B and types A and C.
When would a mutation be considered "good"?
The concentration of free glucose inside a muscle cell is much lower, The patient experiences periods of hypoglycemia, particularly uponawakening
You have just read a paper that the addition of caffeine to cells disrupts the DNA damage checkpoint and you would like to understand why.
Assume the mouse autosomal genes B and S are linked and 38 map units apart. Genotypes B S/B S and b s/b s are intercrossed to produce the F1.
define microevolution. How does the field of population genetics help to describe evolutionary change? How are allele frequencies calculated for a specific gene in a population?
What gametes are possible for a female phoenix whose mother was homozygous dominant for both traits and whose father was homozygous recessive for both traits?
During an action potential, activation of voltage-gated sodium and potassium channels occurs at different rates. What is the effect of this difference on ion flow across an axon membrane?
Unrelated individuals do NOT share ancestors. All of us are related, because we share ancestors. For 2 people to be unrelated there must be 4 parents, 8 grandparents, 16 great grandparents. How many great, great, great grandparents are required fo..
what is the number of homozygous recessive zz individuals showing narcolepsy that you predict in a population of 10,000 that have an allele frequency of 0.9 for the dominant Z allele?
Can enhancers work in trans? That is, can an enhancer on one piece of DNA activate a promoter on another piece of DNA. Propose an experiment to test this. Be sure to discuss any appropriate control experiments.
You genetically engineer nucleoplasmin so that a stretch of amino acids near its C-terminal end is removed. What happens to the resultant nucleoplasmin protein if this altered gene is transfected into an amphibian oocyte and transcribed into mRNA,
According to the function of the genes, are they involved in a specific cellular process? If so what process? Does this make sense for gene expression in cancer?
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