Original hodgkin-huxley model, Mechanical Engineering

1. Plot the functions x1 and x as functions of voltage

2. Assume that you hold the membrane potential V at -120 mV until the system reaches equilibrium (i.e. until dx=dt = 0, where x = (V;m; h; n; a; b;M;H)T ) and that at time t = 0 you suddenly change and hold the value of the membrane potential at a value Vo. Plot the currents IL, INa, IK, IA, ICaT as well as the total current as functions of time for a number of di erent values Vo of you choice in the range -75 to +40 mV.

3. Write an algorithm for numerically approximating the solution to the above model.

4. Using the algorithm you developed in Question 2, illustrate the presence of post-inhibitory rebound (PIR) in the above model.

5. Using the algorithm you developed in Question 2 and assuming that ICaT is completely blocked (i.e. GCaT = 0), construct the gain function of the above model.

6. How does the gain function you constructed in Question 5 di er from the gain function of the original Hodgkin-Huxley model?

Posted Date: 3/9/2013 2:14:06 AM | Location : United States







Related Discussions:- Original hodgkin-huxley model, Assignment Help, Ask Question on Original hodgkin-huxley model, Get Answer, Expert's Help, Original hodgkin-huxley model Discussions

Write discussion on Original hodgkin-huxley model
Your posts are moderated
Related Questions
diff.between direct stress and bending stress

Vernier Calipers: It is used to measure internal as well as outer diameters of an object. There are separate jaws available for inside and outside diameter measurements. It can al

Determine the maximum torque - shaft: Determine the maximum torque that can be safely transmitted by a shaft of 400 mm diameter, if (a) the maximum allowable shear stress i

An amount of air contained in a rigid container is at  T1 = 300 K.  After adding 450 kJ of heat, the air temperature increases to  T2 = 430 K.  Determine the mass of air,  m [kg],

what is hartnell governor

How many types of Foundations are there Foundations are broadly classified into two types, viz., shallow and deep foundations with respect to  the width (B) and depth (D) below

(Rigid body rotation) Derive the equation for the shape of the surface zsurf(rsurf) for a rigid-body rotation of water at angular speed (rad/sec). Follow this process: 1) S

why there is heat is not completely converted into work in ideal case?

Q. What is Injection moulding? An important industrial method of producing articles of thermoplastics is injection moulding. The moulding material is loaded into a hopper from

A jet of water moving at 8 m/sec. impinges on a concave-shaped vane to deflect the jet through 120 o when stationary. If the vane is moving at 5 m/sec., calculate the angle of jet