Original hodgkin-huxley model, Mechanical Engineering

1. Plot the functions x1 and x as functions of voltage

2. Assume that you hold the membrane potential V at -120 mV until the system reaches equilibrium (i.e. until dx=dt = 0, where x = (V;m; h; n; a; b;M;H)T ) and that at time t = 0 you suddenly change and hold the value of the membrane potential at a value Vo. Plot the currents IL, INa, IK, IA, ICaT as well as the total current as functions of time for a number of di erent values Vo of you choice in the range -75 to +40 mV.

3. Write an algorithm for numerically approximating the solution to the above model.

4. Using the algorithm you developed in Question 2, illustrate the presence of post-inhibitory rebound (PIR) in the above model.

5. Using the algorithm you developed in Question 2 and assuming that ICaT is completely blocked (i.e. GCaT = 0), construct the gain function of the above model.

6. How does the gain function you constructed in Question 5 di er from the gain function of the original Hodgkin-Huxley model?

Posted Date: 3/9/2013 2:14:06 AM | Location : United States







Related Discussions:- Original hodgkin-huxley model, Assignment Help, Ask Question on Original hodgkin-huxley model, Get Answer, Expert's Help, Original hodgkin-huxley model Discussions

Write discussion on Original hodgkin-huxley model
Your posts are moderated
Related Questions
Find out the final extension and the work done: Problem:  (i) A spring of stiffness 4 N/cm of extension is extended steadily yet the force of 20 N is reached. Find out th


Q. Explain about Ducts and Flues in steam generators? All air ducts and gas flues connecting the forced draft fan, fan intake silencer, preheater, and transition piece at the g

in concept of continum what is the meaning of upper cure


In most hardware stores, you can find what has known as a Heat Gun. Hold the heat gun about 6 inches away from the acrylic you intend on bending say the bumper on a car. They are p

a) Answer the following equations by Factorization method 10x+y+z =12 ; 2x+10y+z =13 ; 2x+2y+10z=14 b) Apply Gauss-Seidal Iteration method to solve the equations 20x+y-2z

Understanding the Role of Ownership : Before starting a business, entrepreneur should know what is involved in owning a business and what are the roles one will have to play to st

Determine the Wire Drawing - cold drawing processes Similar to above process bars are first pickled, washed and coated to prevent any oxidation. After this rods are passed t

(a) Illustrate why a rich mixture is required for the following (i) idling (ii) sudden acceleration (iii) Maximum power (b) A simple jet carburetor is required to supply 5Kg