Original hodgkin-huxley model, Mechanical Engineering

1. Plot the functions x1 and x as functions of voltage

2. Assume that you hold the membrane potential V at -120 mV until the system reaches equilibrium (i.e. until dx=dt = 0, where x = (V;m; h; n; a; b;M;H)T ) and that at time t = 0 you suddenly change and hold the value of the membrane potential at a value Vo. Plot the currents IL, INa, IK, IA, ICaT as well as the total current as functions of time for a number of di erent values Vo of you choice in the range -75 to +40 mV.

3. Write an algorithm for numerically approximating the solution to the above model.

4. Using the algorithm you developed in Question 2, illustrate the presence of post-inhibitory rebound (PIR) in the above model.

5. Using the algorithm you developed in Question 2 and assuming that ICaT is completely blocked (i.e. GCaT = 0), construct the gain function of the above model.

6. How does the gain function you constructed in Question 5 di er from the gain function of the original Hodgkin-Huxley model?

Posted Date: 3/9/2013 2:14:06 AM | Location : United States







Related Discussions:- Original hodgkin-huxley model, Assignment Help, Ask Question on Original hodgkin-huxley model, Get Answer, Expert's Help, Original hodgkin-huxley model Discussions

Write discussion on Original hodgkin-huxley model
Your posts are moderated
Related Questions
Q.    What is belt? How many types of belt are used for the transmission of power? Sol:   The power or rotary motion from one shaft to the other at a considerable distance is

Working of Clutch : The clutches are operated mechanically through linkages. When operator presses the clutch lever, the pressure on the clutch plates reduces to zero, hence the c

Define the Ideal Surface Roughness The ideal surface roughness represents the best possible finish which may be obtained for a given tool shape and can only be approached if bu


what is the relation ship between tolrancr grade and manufacturing process ?


give me an example of law of superposition

Explain Principal Process for Electro Chemical Machining It is also called electrolytic machining or anodic cutting. This process is quite commonly used for shaping har

a) Describe the role of value engineering in new product design and manufacturing. b) Elaborate the basic concept of Just-in-Time in context of optimization of inventory costs.

Equivalen t force System: An equivalent system for the given system of coplanar forces is the combination of force passing through given point and moment about that point. Th