Give structural reasons for the binding dependence, Basic Statistics

Binding studies were carried out in which heparin was immobilized on the surface of cuvettes. The pH dependence of HPRG binding to heparin was investigated and the results are shown in Figure.

a. How is the binding of HPRG to heparin dependent on pH? Give structural reasons for the binding dependence. The structure of heparin is shown in Figure

2.2. NOTE: Figure also serves as a titration curve for the His residues in HPRG-what is the pKR for these residues? Explain.

1541_blinding curve.png

b. The same binding studies were carried out in which HPRG was reacted with diethylpyrocarbonate (DEPC), a compound that specifically reacts with histidine residues. The reaction is shown in figure. Explain the results.

Posted Date: 3/26/2013 8:19:22 AM | Location : United States







Related Discussions:- Give structural reasons for the binding dependence, Assignment Help, Ask Question on Give structural reasons for the binding dependence, Get Answer, Expert's Help, Give structural reasons for the binding dependence Discussions

Write discussion on Give structural reasons for the binding dependence
Your posts are moderated
Related Questions
What is probability 0.10 called?

Why are Jovian moons more geologically active than small rocky planets? - Ices deform and melt at much lower temperatures than rock, allowing icy volcanism and tectonics at sur

a fair die is thrown 3 times.let X1,X2,X3 denote results of 3 throws.what is the probablity that p[X1>X2+X3]

A source of electrical power. A device or system which delivers electrical and or other types of energy to a corresponding device or system. Are commonly referred to as PSU (Power

what is probabality

03 (a) Explain the term capital rationing and suggest the criteria to be used in ranking projects under capital rationing. (05) (b) There are three projects X Y and Z having follow

Year : 2008 2009 2010 2011 2012 2013 sale : 111 120 114 123 117 126

#how will understand question..moving average method problems for 4yearly&5yearly also

A machine is used for machining of a manufactured product. At the beginning of each business day inspection reveals the machine's condition. There are three possible states: 0, 1 a

An HIV educator wishes to determine whether the method of delivering teaching influences adherence with antiretroviral therapy. She decides to measure adherence as viral load (a r