Losch (1875), for the first time, described the disease symptoms of infection of Entamoeba histolytica. However, it was only in 1903 that Schaudin gave the description of the trophozoite and cyst stages. Schaudin was experimenting on himself. Owing to acute infection of E. histolytica that he acquired during self-experimenting, he died at the young stage of 35.
Figure: Entamoeba histolytica and cyst stage (after Kudo)