Bonferronis approach, Finance Basics

We have 10.000 genes and 4.000 of them are annotated for a certain attribute of interest.

a. If we have a single set of 10 genes, how many of them should be annotated to be considered significant using a p-value threshold of

0.10.

b. If we have 1000 sets of 10 genes and out of the 1000 sets, 100 have all the 10 genes annotated, 100 have 9, 100 have 8, ... and 0 have 0 genes annotated, how many sets would be considered significant using the same p-value threshold and Bonferroni's approach?

c. How many of the 1000 sets would be significant using FDR and the same threshold?

Posted Date: 2/23/2013 1:59:55 AM | Location : United States







Related Discussions:- Bonferronis approach, Assignment Help, Ask Question on Bonferronis approach, Get Answer, Expert's Help, Bonferronis approach Discussions

Write discussion on Bonferronis approach
Your posts are moderated
Related Questions
Imagine Joy is the sales manager in a computer retail company and has summarized for each sales transaction the following information: Sales person Date of sales Uni

what type of assets does Intel own and the most significant asset to the company and why?

Acceptance Rule of IRR IRR will accept a venture if its IRR is higher than or equivalent to the minimum required rate of return such is usually the cost of finance also recogn

on may 1, counts, inc has a balance of $1000 in office supplie. during may the company buys $500 more of the office supplies. on may 31 the company counts the supplies and finds 20

Question 1: (a) (i) What are Asset shares? (ii) State the purpose of calculating Asset shares. (b) Outline the five uses of policy Asset shares? (c) Lif

Suggestion Regarding Credit Limit. Should It Be Approved Or Not, W, Finance

Explain the meaning of Gross and Net Yield While gross yield refers to the yield realized by investor before paying taxes, net yield is what remains with him after paying th

A firm has sales of Rs. 10,00,000. Variable cost is 70%, total cost is Rs.9,00,000 and Debt of Rs. 5,00,000 at 10% rate of interest. If tax rate is 40% calculate:

Government - Measuring Business Performance Government The Government is interested particularly in utility companies as KPLC, KPTC and such will offers public services -

Following details are related to three companies which are identical except in terms of ''''r''''. Company ABC Ltd. MNC Ltd. XYZ Ltd. Cost of capital 10% 10% 10% Earn per Share Rs