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Why does kininogen bind to glycosaminoglycans easily

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Reference no: EM131128722

kininogen which is a lysine-rich protein . Like HRGP , it is able to bind to glycosaminoglycans and antimicrobial, but this binding is far less sensitive to small fluctuations id physiological pH.

1. Why does kininogen bind to glycosaminoglycans easily ?
2. why is the binding of kininogen less sensitive to physiological changes in pH?

Reference no: EM131128722

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