+1-415-670-9189
info@expertsmind.com
Why an increase in constriction of veins
Course:- Biology
Reference No.:- EM13677612




Assignment Help
Expertsmind Rated 4.9 / 5 based on 47215 reviews.
Review Site
Assignment Help >> Biology

1. Why 60 years-old patient HA, who was bedridden for a few days, feels dizzy and experiences significant increase in his heart rate after standing up?

2. What will happen to his systemic arterioles regarding vascular tone changes?

3. Why an increase in constriction of veins and an increase in venous return will help to increase his end-diastolic volume?

4. How did epinephrine release from his adrenal medulla affect his blood supply (perfusion) to his skeletal muscles?

5. If this patient is regularly taking beta-blocker, such as metoprolol, how will this drug affect his sympathetic discharge to the heart, to veins and to arterioles? What changes in his blood pressure can be expected? What advice should be given to this patient?

6. If this patient is regularly taking vasodilator, such as long-acting isosorbidedinitrate (Isordil), how will this drug affect his sympathetic discharge to the heart, to veins and to arterioles? What changes in his blood pressure can be expected? What advice should be given to this patient?

7. If this patient is regularly taking Calcium Channel Blocker (CCB), such as nifedipine, how will this drug affect his sympathetic discharge to the heart, to veins and to arterioles? What changes in his blood pressure can be expected? What advice should be given to this patient?

8. If this patient is regularly taking Angiotensin Converting Enzyme (ACE) inhibitor, such as lisinopril, how will this drug affect his sympathetic discharge to the heart, to veins and to arterioles? What changes in his blood pressure can be expected? What advice should be given to this patient?

9. If this patient is regularly taking Angiotensin Receptor Blocker (ARB), such as losartan, how will this drug affect his sympathetic discharge to the heart, to veins and to arterioles? What changes in his blood pressure can be expected? What advice should be given to this patient?

10. If this patient is regularly taking thiazide diuretic, such as hydrochlorothiazide, how will this drug affect his sympathetic discharge to the heart, to veins and to arterioles? What changes in his blood pressure can be expected? What advice should be given to this patient?

Answered:-

Verified Expert


Preview Container content

ß blocker such as metoprolol are selectively potent against cardiac (ß1) compared to bronchial (ß2) receptors, however this selectivity is lost at higher dose. The sympathetic discharge of the heart is reduced with various protective mechanism such as (i) sub-endocardial coronary flow enhancement, which leads to diastolic prolongation; (ii) restoration of reflex control over heart and circulation; (iii) inhibition of catecholamine cardiotoxic effects and (iv) improved myocardial performance with reduction in heart rate and oxygen demand.

It is noteworthy to mention that the chronic usage of ß blocker – metoprolol is likely to improve the performance of left ventricle and reverses the left ventricle remodeling. The oxygen supply to the myocardial is improved, which also increases the exercise tolerance. These condition leads to improved patient ß blocker such as metoprolol are selectively potent against cardiac (ß1) compared to bronchial (ß2) receptors, however this selectivity is lost at higher dose. The sympathetic discharge of the heart is reduced with various




Put your comment
 
Minimize


Ask Question & Get Answers from Experts
Browse some more (Biology) Materials
Other pol A mutants of E.coli lack 3'----->5'exonuclease activity of DNA polymerase I. Will the rate of DNAsynthesis be altered in these mutants? What effect (s) will thesep
Compute the number of molecules of gramicidin in eight ml of a 50nM solution. Suppose the same fraction of gramicidin remains as part of the membrane as the fraction of lipids
What are some of the possible benefits of recombinant DNA technology and genetic engineering? What are some of the potential drawbacks?
The hydrologic cycle is made of several factors. The water on the earth's surface mainly from oceans is released by evaporation and transpiration. As the water travels up into
A novel fungicide is introduced and widely applied to cereal crops. After five years, resistant genotypes of the fungal pathogen are detected at a frequency of about 1%; res
Determine the final guaiacol concentrationg of the following enzyme reaction solutions listed in the table below. Keep in mind that each reaction solution has a total volume o
Organisms have evolved physiologically and anatomically to adapt to their environment. Select one species from the text or another source. How have their traits evolved by n
Think about an experimental Drosophila population containing 5 males and 5 females (2N = 20) in a population. An autosomal locus (gene A) has allele A1 and A2 with frequencies