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Sketch a block flow diagram of the process

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Cyclosporine A is produced by fermentation using either Cylindrocarpon lucidum Booth or Tolypocladium inflate Gams. The fermentation is carried out in batch reactors, which are filled with a feed medium, inoculated with the fungi, and aerated for a period of 13 days. The reactor product is milled and extracted with 90% methanol. The methanol is evaporated off to give an aqueous solution that is then extracted with ethylene chloride. The organic solution is evaporated to dryness and then the product is purified by chromatography in methanol over aluminum oxide or silica gel. Sketch a block flow diagram of the process.

Reference no: EM13884189

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