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Question: Most human obesity does not follow Mendelian inheritance patterns, because body fat content is determined by a number of interacting genetic and environmental variables. Insights into how specific genes function to regulate body fat content have come from studies of mutant, obese mice. In one mutant strain, tubby (tub), obesity is inherited as a recessive trait. A comparison of the DNA sequence of the tub+ (wild-type allele, or the nonmutated allele) and tub alleles has revealed a single base-pair change: within the transcribed region, a 5' G-C base paur has been mutated to a T-A base pair. The mutation causes an alteration of the initial 5' base of the first intron. Therefore in the homozygous tub/tub mutant, a longer transcript is found. Propose a molecular based explanation for how a single base changes causes a nonfunctional gene product to be product, why a longer transcript is found in the tub/tub mutants.
You want 1 L of 100 mu M NaCl, and you have 1 M stock solution. How much of the stock solution and determine how much dH2O will you measure out for this dilution?
Animals obtain energy during a sequence of chemical reaction in which sugar (C6H12O6) and oxygen gas (O2) are reactants. This process produces water (H2O) and carbon dioxide (CO2) as waste products. How might you use radioactive isotope to find out w..
Estimate joints are moving in a forward lunge and what muscles are involved? What type of movement is occuring.
Describe why an anaerobic indicator strip in an anaerobic environment will revert to blue if it gets wet.
Determine which mode of inheritance produces heterozygotes with phenotypes that differ from homozygote but more closely resembles one homozygous phenotype than other?
The energy of the reactants of the reaction are indicated through the vector labeled and the change in the free energy of the reaction is labeled.
The "Primordial soup" includes the mixture of elements and gases which are thought to have started life on the Earth. Speculate on how, over the course of evolution, these complex molecules would eventually form the complex life forms such as human..
define how prokaryotes and eukaryotes provide different. What does each category tell you about evolution; pick one from an early era and one from today or recent times.
How may you use site-directed mutagenesis to determine whether this residue is essential for proton conduction?
Hermann Kolbe's synthesis of an organic compound, acetic acid, from inorganic substances that had been prepared straight from pure elements was an important milestone for what reason.What piece of evidence contradicts this claim.
Explain the circuitry and function of the cerebellum. Next, explain one of the following: a trained baseball player who is interfering with his swing by over-thinking it,
Which of the statements best describes the shape of its teeth? How many teeth does it have in the premaxilla.
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