How many copies of the represor would required

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Reference no: EM13161373

A typical bacterial repressor protein discriminates between its specific DNA binding sites (operator) and nonspecific DNA by a factor of 10^4 to 10^6. About 10 molecules of repressor per cell are sufficient to ensure a high level of repression. Assume that a very similar repressor existed in a human cell, with a similar specificity for its binding site. How many copies of the represor would required to elicit a level of repression similar to that in the bacterial cell? (Hint: The E. Coli genome contains about 4.6 million bp; the human haploid genome has about 3.2 billion bp.)

Reference no: EM13161373

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