+1-415-670-9189
info@expertsmind.com
Describe the mechanism of action of eicosanoids
Course:- Biology
Reference No.:- EM13670980




Assignment Help
Assignment Help >> Biology

1. Present the comparison of neuromuscular blocking drugs and local anesthetics. What is a rationale to use them for pain control?

2. Present the rationale for clinical applications of COX inhibitors. What is a difference between COX-1 and COX-2 activity blocking drugs? How can they be used in clinical practice?

3. Describe the mechanism of action of eicosanoids. Give examples of eicosanoids used to treat bronchoconstriction and inflammatory cell infiltration of the bronchi.

Answered:-

Verified Expert


Preview Container content

Neuomuscular blocking agents and local anesthesia comes under the category of skeletal muscle relaxants. Particularly, the neuromuscular blocking agents are referred to as competitive and depolarizing blockers. Neuromuscular blocking agents act by blocking the neuromuscular transmission particularly at the junction. This is mediated with either inhibition of the synthesis of acetylcholine or via acting at the post-synaptic terminal end of motor nerves of the acetylcholine receptors. Depolarizing agents use to bind with the cholinergic receptor and causes the depolarization of the endplate membrane

Followed by a blockade in the neuromuscular transmission. On the contrary, nondepolarizing agents causes competitive inhibition of the cholinergic receptors at motor endplate, thereby causing either obstruction to the ion channels or restricting the conformational changes in the receptor to generate any action potential. The clinical use of these agents lies in context to the relaxation of the skeletal muscles that permit many of the important health care related activities. These include intubation of the tracheal tube, surgery and inhibition of spontaneous




Put your comment
 
Minimize


Ask Question & Get Answers from Experts
Browse some more (Biology) Materials
The antibiotic, polymyxin B, attaches itself to the phospholipids in the bilayers of bacterial cells and increases the permeability of the membrane. What is a likely result
Will the employee or licensee assist in protecting the IP by applying for a copyright, patent, trademark, or any other type of protection?  This is important as in many situ
If there was mutation in a dna triplet that changed the first triplet from ctt to ctc, would that cause the problem with the resulting polypeptide.
How many different proteins, each with a unique amino acid sequence, can be constructed with a length of five amino acids? Thats all the information given in the question. N
Create and observe bacteria in petri dishes for my own learning experience. I thought I was being sufficiently sanitary while heating the agar and pouring it into the plates.
The sulfur reduction test is not able to differentiate H2S produced by anaerobic respiration and H2S produced by putrefaction. Is this inability the result of poor sensitivi
A new recessive mutation in chickens that causes feather loss from the wings is being investigated. Describe the expected progeny phenotypes from a cross between a hen with
The autosomal recessive gene transformer (tra) mutation converts chromosomal females into sterile males. A female Drosophila that is heterozygous for the tra allele is mated w