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A male volunteer named Conan was passively sensitized with IgE specific for Der f 1 (a potent house dust mite antigen/allergen). After an intradermal challenge with Der f 1, Conan displayed a typical skin lesion due to an immediate hypersensitivity reaction. Assess as either factually correct (= "true") or incorrect (= "false") the hypothetical results (11-20) obtained if the injection with sensitizing IgE was first preceded by an injection (at the same site) of Fc fragments of human IgE and then followed by the intradermal injection of allergen (Der f 1):11. The reaction would be exacerbated due to the increased local concentration of IgE Fc fragments.12. The reaction would be exacerbated due to the activation of complement.13. The reaction would be exacerbated due to the augmented release of cytokines.14. The reaction would be exacerbated due to the activation of macrophages and dendritic cells. 15. The reaction would be exacerbated, because the Fc fragments would activate NK cells.16. The reaction would be exacerbated, because the Fc fragments would activate mast cells and/or basophils.17. No reaction would occur because the Fc fragments would interact with the allergen and prevent it from gaining access to the sensitized mast cells.18. No reaction would occur because the Fc fragments would interact with the IgE antibodies making their antigen-binding sites unavailable for binding to antigen.19. No reaction would occur because the Fc fragments would interact with Fc? receptors on mast cells.20. Conan would develop anaphylaxis.
In a pathway controlling flower color, a functioning copy of gene A is required to produce enzyme A, which catalyzes the synthesis of red pigment.
Biotechnology permits the use of living organisms or their processes for human needs or purposes. Currently, this topic includes such general examples as cloning,
Describe the three kind of the recombination among microorganisms. DNA is transferred horizontally among same generation. The phenotype of gene at end of recombination will be changed.
Use living organisms to control pests are often used in many nations. What factors must be taken into account in using fungi to combat agricultural pests?
I have 30µg of a primer, whose molecular weight is 600. Determine how much water should I add to get a stock primer concentration of 100µM?
Think about the following two unlinked genes in the poisonous plant, Jimson Weed. The dominant allele V produces violet petals while the recessive allele v produces white petals.
It is January and the starting of a new semester. Just as you get settled in to your new routine, you begin to notice that illness is spreading across campus and other students in your classes are so sick they do not come to virology class.
After one minute, ask your subjects to close their eyes. Once their eyes are closed, ask them to recite everything in the room that is different colour than the one they were looking for, for in case, anything and everything that is green.
The global community is plagued by increasing incidence of lung cancer, colorectal cancer, breast and pancreatic cancers, prostate cancer, leukemia, non-Hodgkin lymphoma, liver, ovarian and esophageal cancers.
A major evolutionary trend among plants is: A reduction in size of the gametophyte and an increase in size of the sporophyte. A reduction in size of the sporophyte and an increase in size of gametophyte.
Using examples, discuss types of genetic mutations that result in faulty proteins and disease,
If a population with two alleles is at Hardy-Weinberg equilibrium and the frequency of one allele is 0.6, what is the heterozygote frequency.
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