Rate of the triose phosphate iso- merase reaction

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Reference no: EM13310994

The pH dependence of the rate of the triose phosphate iso- merase (TIM) reaction has characteristic pK’s of 6.5 and 9.5. His 95, a catalytically essential residue, has been shown to have a pK of 4.5. Why doesn’t the pH rate curve indicate the existence of this pK?

Reference no: EM13310994

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