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Q. Your friend is studying mouse fur color and has isolated the GPCR responsible for determining its color, as well as an extracellular signal that activates the receptor. She finds that, on adding up the signal to pigment cells (cells that produce the pigment determining fur color), cAMP levels rise in the cell. She starts a biotech company, and the company isolates more components of the signaling pathway responsible for fur color. Using transgenic mouse technology, company genetically engineers mice that are defective in various proteins involved in determining fur color. The company obtains the follow results.
Normal mice have beige (very light brown) fur color.Mice lacking the extracellular signal have white fur.Mice lacking the GPCR have white fur.Mice lacking cAMP phosphodiesterase have dark brown fur.
Your friend has also made mice that are defective in α subunit of the G protein in this signaling pathway. The defective α subunit works normally except that, once it binds GTP, it cannot hydrolyze GTP to GDP. What color do you guess that the fur of these mice will be? Why with reason?
Explain the outcome/result as Alu TE is integrated into the coding region of a gene. Illustrate the mechanism of Alu TE integration.
Frank found himself in the midst of an ethical dilemma at work, and was using an ethical decision-making matrix, to address his work and personal values. Frank was most likely in which phase of the Ethical Decision-Making Framework.
Cyanobacteria grow prolifically in streams and lakes with low oxygen levels and high nutrient concentrations. How may the presence or absence of cyanobacteria be used as an index of pollution in lakes.
What will the instructor tell the students are the most ordinary cause of an MI.H ow various different antibody molecules potentially could be generated.
Write a scientific review of membrane proteins
What combination(s) of chromosomes are possible in haploid cells following both divisions of meiosis? (Hint: remember independent assortment). A diploid cell contains three pairs of homologous chromosomes designated C1 and C2, M1 and M2, and S1 and S..
The tRNA in the E site will leave and migrate to its aminoacyl-tRNA synthetase d. where the tRNA will be recharged with the correct amino acid.
What phenotypes will you suppose among the 1024 offspring, and how many of each phenotype would you expect.Suppose that a cross is made between a fly with normal wings.
What specific effects might these toxins have on neuron function. How various plants of each of the four phenotypes do you expect.
Explain why bacteria do not have apoptotic signaling pathways.
What would occur to the preferred habitat of your plant (Red Maple) in case of partial water drainage of the Mer bleue marsh (such as the water level would go down half the depth of the marsh).
Which of the follow statements regarding cancer risk factors is false. Mutagens are generally not carcinogens.
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