How to enhance this effect of acetylcholine

Reference no: EM137044

Q. Acetylcholine acts at the G-protein-linked receptor on heart muscle to make the heart beat more slowly by the effect of the G protein on a K+ channel. Which one or more of next would enhance this effect of acetylcholine? Explain your reasoning to all answers.

(a) A high concentration of a non-hydrolyzable analog of GTP.

(b) Modification of acetylcholine-receptor-linked G protein α subunit by cholera toxin.

(d) Mutations in acetylcholine receptor that weaken the interaction between the receptor and the G protein.

(e) Mutations in the G protein β subunit that weaken the interaction between βγ and K+ channel.

Reference no: EM137044

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