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The agouti locus in mice has three alleles: a is recessive and confers a black coat, A is dominant to a and confers an agouti coat, and AY is dominant to both and confers a yellow coat. AY is also a recessive lethal. In addition, the independently assorting c allele is recessive (to C) and prevents the mice from making any fur pigments at all, whether yellow, agouti or black. Two mice are crossed, and produce offspring in a ratio of 1 albino : 2 yellow : 1 black. What are the genotypes and phenotypes of the parent mice?
A female has alleles C and H on one homolog, and c and h on the other. What kinds of eggs can she make if the genes are so close together that there is no crossing over between them.
Interestingly after activation of the rtk by your antibody you notice that the downstream effects are different than the effects seen with the normal ligand for that receptor. Describe at least one way that this may be possible.
define the structure and function of deoxyribonucleic acid (DNA) as the molecule of inheritance.
Unexpectedly, a missense mutation found in a protein-coding gene is no longer causing problems for the cell due to the presence of this mutant tRNA. Before the missense mutation in the protein-coding gene, what was the unique encoded amino acid.
If you were to mix the primer and template DNA shown below , along w/ a DNA polymerase and all 4 DNTP's . Recreate the template with the primer hybridized to it.
Explain what is meant through a negative feedback loop and how these work in terms of regulating a metabolic pathway. provide an example of a negative feedback loop in the glycolytic pathway.
Explain why are both recombination maps and physical maps important and what are the differences between them?
What are the expected frequencies of three phenotypes (bald, red hair, yellow hair) in the male offspring of this cross? Imagine we observe 50 percent bald, 42 percent yellow hair, and 8 percent red hair. What is a recombination fraction between the ..
If given this in this sequence to find surface area, 1 cm x 2 cm x 2 cm block, am I to assume it is written in LxWxH format?
For the purpose of thinking about the genetics of the cross you've made, call the two microsatellite markers A and B. You can then designate the alleles A1, A2, A3, and A4 for the A allele and B1 through B6 for the B marker.
Determine what is the most common mechanism for repairing damage to DNA? Individuals with xeroderma pigmentosum inherit a faulty DNA repair mechanism.
How does digestion progress once a carbohydrate reaches the small intestine, and what substances must be released from the pancreas to allow digestion to continue?
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