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Tetracyclines and organic compounds
Stephen Allen,
another one - I have started this one but have become lost.
identify organic compounds in medications.
determine the structure of one active component and identify three functional groups on each molecule. Based on the functional groups present in the drug molecules, predict the physical properties of the molecule the drug would interact with. This gets the "molecularity" of the drug interaction.
Tetracycline has 4 functional groups: alcohol, ketone, amine, and amide. It also contains aromatic rings. Amine group is a base because it accepts H+ when dissolved in water. Beause amines are bases they react with acids. Amides are not bases because of the highly electronegative oxygen atom of the of the carbonyl group causes a very strong attrcation between the lone pair of nitrogen electrons and the carbonyl group. As a result, the unshared pair of electrons cannot "hold" a proton. Alcohols are very polar and are able to form intermolecular hydrogen bonds.
Lead metal is added to 0.100M Cr3+(aq), Pb(s) + 2Cr3+(aq) -> Pb2+(aq) + Cr2+(aq)
which is limiting reagent when 42.0g of propane , C3H8, is burned with 115g of oxygen ? how many liters gaseous water are produced at STP
How many grams of CaH2 are needed to generate 19.0 L of H2 gas if the pressure of H2 is 780. torr at 15 C?
A 270- flask contains pure helium at a pressure of 755 . A second flask with a volume of 485 contains pure argon at a pressure of 727 torr.
The combustion of butane produces heat according to the equation 2C4H10(g) + 13O2(g) -> 8CO2(g) + 10H2O(l) ->H°rxn = -5,314 kJ/mol What is the heat of combustion per gram of butane
What molar ratio of sodium acetate to acetic acid should be used to prepare a buffer with pH = 4.5? Ka acetic acid = 1.8 x 10-5.
Wind provides a source of renewable energy that is increasingly being tapped. Modern wind tubines can conbert up to 30% of the kinetic energy of the incoming wind blowing through their blades to electicity.
Calculate the molar concentration of OH - ions in an 1.37 M solution of hypobromite ion, BrO- (Kb = 4.0 10-6).
Understanding of chemistry basics - which of the following is not changed by the activity of an enzyme during a chemical reaction?
The reaction of 0.130 moles of a metal with an acidic aqueous solution in a calibrated calorimeter causes the temperature to increase by 49.0°C.
how many milliliters of a stock solution of 2.00 m kno3 would you need to prepare 100.0 ml of 0.150M KNO3
if the height of the mercury column in a leveling bulb is 30 mm greater than that in the gas buret and atmospheric pressure is 670 mm, what is the pressure on the gas trapped in the buret.
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