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1. As a Nursing student in Advanced Human Anatomy, you were able to observe a total hip replacement. While the O.R. personnel where prepping the patient for the surgical procedure, the anesthesiologist assumed (rightly so!) that you had some physiology background. As such, she launched into the following procedural explanation: The patient will need to be intubated, therefore he will be given a single dose of the neuromuscular blocking agent, succinylcholine to provide muscular relaxation during the surgery and to facilitate the insertion of the endotracheal tube. The anesthesiologist asked you the following:
a) Beginning with depolarization at the neuromuscular junction, describe the normal sequence of events which lead to muscle contraction. (10)
b) What prevents acetylcholine (ACh) from accumulating in the neuromuscular junction and causing a sustained contraction in a normal individual? (3)
c) Succinylcholine acts as a depolarizing agent that prevents repolarization of the nerve. Therefore, no further ACh is released until the drug is cleared. Name another site within the neuromuscular junction that might be affected to prevent muscle contraction. (Hint: curare acts by this mechanism) (2)
Determine which chemical groups of nucleotides react to form a covalent phosphodiester bond?
Explain a specific example of a cross in two parents, each homozygous for different traits, which would result in a phenotype that is distinct from either parental phenotype.
Phenylalanine deaminase positive and phenylalanine deaminase negative culture. Determine the purpose of the uninoculated control? What other types of controls would be useful to increase reliability of the test?
A five year old girl displayed increased apetite, increased urinary frequency and thirst. Her physician suspected new onset diabetes mellitus & confirmed that she had elevated urine glucose and ketones.
There are forty chromosomes in somatic cells of the house mouse. how many chromosomes does a mouse receive from its father and how many autosomes are present in a mouse gamete?
Analyze the DNA of the Phenylalanine hydroxylase gene in patient with phenylketonuria revealed a mutation in protein coding region whose predicted effect would be to replace the amino acid aspartic acid, with histidine.
How might you deterine whether the turbidity in your nutrient broth tube was from a mixture of different microbes or from the growth of only one kind of microbe.
The U.S government has placed this strain of C.taxifolia on noxious weed list, which means that any possible source of the contamination of the weed will be highly restricted. Shipments that contain any kind of C.taxifolia and pass through an area wh..
The target of the project is for you to evaluate the effect of an acid on enzymatic activity. As part of this project, you must identify your source of enzyme and the acid used.
You have read that inorganic fertilizers contribute to water pollution and would like to make a switch from inorganic fertilizers to organic compost in your vegetable garden.
After phagocytosis of a pathogen, the phagosome becomes very acidic with the pH dropping to between 3.5 and four. However, some of the enzymes are important to kill pathogens only work when the pH is higher than five.
Large folds in the stomach known ______ increase its surface area and also enable it to fold on itself when empty. The ______ is a valve that enables partially digested food out of stomach into the ______.
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