Zoonoses disease- colibacillosis, Biology

Colibacillosis
Colibacillosis is caused by different strains of Escherichia coli. The disease mainly affects children and travelers. Organisms grow in gut and produce toxin. It may also invade superficial epithelium.


Epidemiology: On the basis of virulence and disease manifestations, 6 distinct groups of E. coli have been described. They are enterotoxigenic (ETEC), enteroinvasive (EIEC), enterohaemorrhagic (EHEC), enteropathogenic (EPEC), enteroaggregative (EaggEC) and diffusely adhering (DAEC) E. coli. Among EHEC, serotype 0157:H7 has emerged as a major pathogen. EPEC is an important cause of infantile diarrhoea and ETEC is the most common cause of traveler’s diarrhoea. EIEC produces an invasive dysentery type of diarrhoeal illness in humans with similar pathogenesis to Shigella.


Clinical features:
Incubation period is 24-72 hours. Toxin causes hyper secretion of chloride and water in small intestine. Sudden onset of diarrhoea and/ or vomiting occurs. It is a serious infection in newborn and an important cause of traveler’s diarrhea in adults. The disease is self-limiting and takes 1-3 days for recovery.


Diagnosis:
Diagnosis can be done based on isolation and identification of the b a c t e r i a  a nd  se r o l o gi c a l  te s t  l ik e  in d ir e c t  ha e ma g gl u ti n a t i o n .  M U G  (4 - methyleumbelliferyl-â-D-glucuronide) sorbitol agar is used for selective isolation of E. coli 0157:H7.Detection of virulence genes of pathogenic E. coli by PCR is a rapid and reliable technique. PCR based detection techniques have made it possible to detect genes encoding enterotoxins, cytotoxins and adhesion factors in E. coli strains.


Control and prevention:
Prevention can be done by providing public health education for adopting necessary hygiene and environmental sanitary practices. Thorough cooking of food and safe drinking water are essential to check such food- borne infections.

Posted Date: 9/20/2012 2:44:57 AM | Location : United States







Related Discussions:- Zoonoses disease- colibacillosis, Assignment Help, Ask Question on Zoonoses disease- colibacillosis, Get Answer, Expert's Help, Zoonoses disease- colibacillosis Discussions

Write discussion on Zoonoses disease- colibacillosis
Your posts are moderated
Related Questions
Explain Technical factors influencing food production? Improvement in technology has a significant impact on productivity. Improvements may occur in seed production, fertilizer

Sour taste is usually due to the presence of acids such as acetic acid, citric acid, benzoic acid. Upon dissociation, the acids give H ions which impart acidity. More the H ion con

What are the benefits of high-throughput expression analysis in molecular biological investigations? Ans) These methods permits simultaneous analysis of the expression of a lot

How do you draw in organic chemistry format a carbon double bonded to an oxygen atom when this carbon is the first carbon on a carbon skeleton of a molecule?

Preparation on the Morning of Surgery Morning care  Hygiene Bowel and bladder emptying.  Oral hygiene, remove dentures if any, no lipstick.  Comb and make th

How do the ideas of energy and chemical cycles, community structure, biodiversity and succession fit together to form the basis of the way the natural world works?

Q. List various type of insulin? Types of insulin: a) Rapid or Short acting b) Intermediate c) Combination d) Long acting

Explain the difference among a sex-linked trait and a sex-influenced trait. A sex-influenced trait is influenced by the presence of sex hormones and its genes are not situated

1)  You want to clone the arg3 gene, which encodes an enzyme in the arginine biosynthetic pathway in Neurospora crassa.  You have available the E. coli plasmid vector shown in part

Ask Prepare a 2-4 page summary of nucleic acid amplification techniques that are being explored in the development of nucleic assays for clinical use. Research and identify a mo