Thalassemia, Biology

Thalassemia 

Thalassemias are the commonest hemolytic anaemias or disorder seen in children in India. This is characterised by deficiency  in the synthesis  of one of the normal globin chains of haemoglobins and there is an increased synthesis of foetal haemoglobin (HBF) which alters the ratio of adult and feral haemoglobin.

Two common types of thalassemia are caused by decrease in alpha or beta chains.

Two major form of beta thalassemia are thalassemia minor and thalassemia major. 

Thalassemia minor is associated with decreased beta chain synthesis and is the heterozygous  form of the disease which generally produces little effect on the child except mild anaemia. 

Thalassemia major (Cooley's anaemia, mediteranean anaemia) is associated with absent beta chain synthesis and is the homozygous form of the disease and produces severe anaemia. This is the commonest form of thalassemia.  

Posted Date: 10/26/2012 9:21:56 AM | Location : United States







Related Discussions:- Thalassemia, Assignment Help, Ask Question on Thalassemia, Get Answer, Expert's Help, Thalassemia Discussions

Write discussion on Thalassemia
Your posts are moderated
Related Questions
Asexual Reproduction Asexual reproduction is also known agamic reproduction because there is no involvement of gametes in it. Asexual methods of reproduction are

In the hybridization of 2 genes (4 different alleles, 2 of each pair) how does epistasis affect the proportion of phenotypical forms in the F2 generation? In the dihybridism wi

How Cycling is beneficial for proper health Cycling is best for maintenance of fitness. It is a popular exercise and can be done by individual of all ages. Bicycle is required

What is the function of the left ventricle? Where does the blood go after leaving the left ventricle? The function of the left ventricle is to get blood from the left atrium an

Explain the Uses of ISO in Seafood products  Seafood products  The most significant application in this category is the use of ISP in fish sausage and surimi based restructu

Define Food Effects in the Survival & Growth of Microorganism? Nature of the food also affects the microbial survival and growth. Each food has its own characteristics which de

Q. Show the Artificial Keys? These are based on the resemblances and differences of some prominent characters in the taxa. These are based on the phylogenetic relationship b

Q. What is the morphological characteristic that evolutionarily approximates the beings of the phylum Annelida to arthropods? The metameric feature that is the body segmentatio

Triacylglycerols are synthesized from fatty acyl CoAs and glycerol 3-phosphate.The   glycolytic   intermediate   dihydroxyacetone phosphate   is   first reduces   to glycerol   3-p

An incubation  combination  is set up having  the single-stranded  DNA template, DNA polymerase  I, the primer and all 4 deoxyribonucleoside triphosphates (dTTP, dGTP, dCTP, dATP),