Scrapie, Biology

Scrapie

This is a chronic fatal disease of sheep and occasionally of goats caused by a Prion agent similar to BSE. The disease is reported from Europe, North America and in a few countries of Africa and Asia.

Clinical signs: Incubation period is of 2-5 years. Affected sheep show excitement, signs of muscular tremors of head and neck, wavering gait, vacant look and paraplegia. Sheep develop pruritus with wool loss and skin rubbed raw. They loose weight and ultimately die.

Diagnosis: The disease is diagnosed by the clinical signs, direct electron microscopy of brain material or demonstration of Prion protein by Western blot. The agent can be transmitted to mice and hamster and these species are being used as laboratory models for characterizing the agent.


Prevention and control:
The disease is controlled by systematic detection of infected  and in-contact animals and their disposal by slaughter and consequently building disease free "certified flocks".

Posted Date: 9/18/2012 7:13:22 AM | Location : United States







Related Discussions:- Scrapie, Assignment Help, Ask Question on Scrapie, Get Answer, Expert's Help, Scrapie Discussions

Write discussion on Scrapie
Your posts are moderated
Related Questions
How do you determine net atp production after complete oxidation to CO2 and H2O using mitochondrial?-oxidation, the TCA cycle, the mitochondrial electron transport chain and oxidat

Determine Energy demand for Vigorous or vigorously active lifestyles? These people engage regularly in strenuous work or in strenuous leisure activities for several hours. Exam

Processes in Succession - Ecology Whether succession is primary or secondary, in terrestrial or aquatic ecosystems, the basic processes involved in succession are similar. The


Carbohydrates These form about 1%part of protoplasm, they are comparatively simpler compounds of carbon, hydrogen and oxygen in the ratio 1:2:1 The ratio hydrogen to oxygen is

Under which form is nitrogen fixed by living beings? Most living beings cannot use molecular nitrogen to get nitrogen atoms. Producers fix nitrogen mostly from nitrate (NO3-).

KIDNE Y (RENAL FAILURE) - RF - Partial or total inability of kidney to carry excretory functions is called RF. It leads to uremia (excess of urea in blood), salt-water imba

Explain Metabolic Requierments For Types Of Exercise ? A relative scale of energy requirements related to heart function necessary for performing various daily activities has b

Define Patient Education for preventive strategies for food allergy? Patient education, therefore, is critical and should include: Allergen identification (e.g., how to

information on some heterotrophic plants