Scrapie, Biology

Scrapie

This is a chronic fatal disease of sheep and occasionally of goats caused by a Prion agent similar to BSE. The disease is reported from Europe, North America and in a few countries of Africa and Asia.

Clinical signs: Incubation period is of 2-5 years. Affected sheep show excitement, signs of muscular tremors of head and neck, wavering gait, vacant look and paraplegia. Sheep develop pruritus with wool loss and skin rubbed raw. They loose weight and ultimately die.

Diagnosis: The disease is diagnosed by the clinical signs, direct electron microscopy of brain material or demonstration of Prion protein by Western blot. The agent can be transmitted to mice and hamster and these species are being used as laboratory models for characterizing the agent.


Prevention and control:
The disease is controlled by systematic detection of infected  and in-contact animals and their disposal by slaughter and consequently building disease free "certified flocks".

Posted Date: 9/18/2012 7:13:22 AM | Location : United States







Related Discussions:- Scrapie, Assignment Help, Ask Question on Scrapie, Get Answer, Expert's Help, Scrapie Discussions

Write discussion on Scrapie
Your posts are moderated
Related Questions
Explain the Properties gum karaya Gum karaya is water-swellable rather than water-soluble and absorbs water very rapidly to form viscous colloidal dispersions at low concentra

Posaconazole  Posaconazole (SCH 56592), an unapproved azole available from the manufacturer for compassionate use, isunder review by the FDA for oral treatment of invasive fung

Q. Which is the typical feature of the hookworms related to the way they obtain food and explore the host? Both The Necator americanus and Ancylostoma duodenale have mouthparts

Explain the Membrane Equilibria? A semipermeable membrane used to separate two liquid phases can, in principle, be permeable to certain species and impermeable to others. A mem

who proposed the trinominal nomenclature

Explain the Sporangiophores features of Rhizopus? 1. Sporangiophores swell at the tip into a spherical knob like structure called sporangium. It has two zones. - Central dom

you tested three different treatments for ripening bananas. Before you did the lab, which one did you think would have ripened most? State your hypothesis and explain your reason

Pesticides - Danger to Wildlife Another recently realised danger to wildlife in many parts of the world has come from the development of more effective pesticides. As agricult

Explain the Community ecology of disease? Ebola, hantavirus, bubonic plague, Lyme disease, West Nile virus, rinderpest, and canine distemper virus are all instances of diseases

Q. How many chromosomes does a human normal diploid cell have? How many chromosomes does a human normal haploid cell have? How many are the sex chromosomes within each of them?