Scrapie, Biology

Scrapie

This is a chronic fatal disease of sheep and occasionally of goats caused by a Prion agent similar to BSE. The disease is reported from Europe, North America and in a few countries of Africa and Asia.

Clinical signs: Incubation period is of 2-5 years. Affected sheep show excitement, signs of muscular tremors of head and neck, wavering gait, vacant look and paraplegia. Sheep develop pruritus with wool loss and skin rubbed raw. They loose weight and ultimately die.

Diagnosis: The disease is diagnosed by the clinical signs, direct electron microscopy of brain material or demonstration of Prion protein by Western blot. The agent can be transmitted to mice and hamster and these species are being used as laboratory models for characterizing the agent.


Prevention and control:
The disease is controlled by systematic detection of infected  and in-contact animals and their disposal by slaughter and consequently building disease free "certified flocks".

Posted Date: 9/18/2012 7:13:22 AM | Location : United States







Related Discussions:- Scrapie, Assignment Help, Ask Question on Scrapie, Get Answer, Expert's Help, Scrapie Discussions

Write discussion on Scrapie
Your posts are moderated
Related Questions
Which of the following is the best definition of the initiation delay that is seen in all organisms? A. Initiation delay is explained as the time it takes for the pre-initiatio

What is the phenomenon known as "red tide"? Which ambiental harms can it cause? Red tide is a phenomenon that happens when dinoflagellates (algae from the pyrrophyte group) pro

A genomic DNA library is made from the genomic DNA of an organism. For instance, a mouse genomic library could be made by digesting mouse nuclear DNA with a restriction nuclease to

What does vacuoles do? It is an organelle, located in the cell's cytoplasm, which is the site of protein synthesis. It is really a protein having of 2 parts. These 2 "parts"

Describe how electro negativity can explain why a C-H bond is a no polar covalent bond, but a O-H bond is a polar covalent bond.

what is he importance of proteins for living beings

Q. Fats requirements for ulcerative colitis? Usual foods, which contain fats (invisible or inherent fat), are permitted but not fried foods, as they are not easily digested due

Determine the Food Sources of Pyridoxine? Raw foods contain more of this vitamin than cooked foods. The food sources include: 1. Rich sources: Rice polishing s, wheat bran,

Brackish Water The content of dissolved salts in brackish water is higher than the fresh water and ranges between 0.5 to 35%. These waters of intermediate salinity range are d

Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4