Role of nerves - regeneration, Biology

Role of Nerves - Regeneration

It has been seen that soon after amputation nerves invade the regeneration blastema. If the stump is denervated by cutting the nerves supplying the limb as they come out from the spinal cord, and are avoid from regrowing into the site of amputation them regeneration fails to take place. The apical cap is not formed. In larval urodeles, denervation results in large scale regression of stump tissues and the whole limb stump may disappear. If the nerve fibers are allowed to regrow into the stump earlier than a thick skin forms on the wound surface regeneration may be re-initiated. These studies have displayed with certainty that the existence of nerves is essential for regeneration of the limb.

A number of experimental studies have been made to know the nature and mechanism of nerve influence on limb regeneration in urodeles. The nerves are believed to generate a "trophic influence" on the blastema cells of the regenerating limb. This neurotrophic effect has been emerge to be produced by all nerves, if motor or sensory or central irrespective of whether they have functional relationship with the central nervous system or not. Grafting of spinal ganglia in the regenerating area of limbs, whose own nerves have been cut and severed, also promote regeneration. Though, it has been found that the presence of a minimum number of nerve fibers is essential for regeneration. Below this threshold regeneration does not take place.

Posted Date: 1/31/2013 4:47:25 AM | Location : United States







Related Discussions:- Role of nerves - regeneration, Assignment Help, Ask Question on Role of nerves - regeneration, Get Answer, Expert's Help, Role of nerves - regeneration Discussions

Write discussion on Role of nerves - regeneration
Your posts are moderated
Related Questions
Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Is herbivorism a form of predatism? Herbivorism is a type of predatism in which first order consumers feed from producers (plants or algae). For instance, birds and fruits, hum

What are DNA ligases? How do these enzymes participate in the recombinant DNA technology? The DNA ligases are enzymes specialized in tying the complementary DNA chains that for

Q. Briefly explain about Type Specimens ? The specimens on which the names of the species are based are kept as type specimens. Do not replace these specimens because these wi

Q What are the three major types of nitrogen wastes excreted by living beings? The main nitrogen wastes excreted by living beings are ammonia, urea and uric acid. Living beings

How does bisulfite sequencing work ?


Determine the Food Sources of Pyridoxine? Raw foods contain more of this vitamin than cooked foods. The food sources include: 1. Rich sources: Rice polishing s, wheat bran,

Determine the Syndrome of Listeriosis Syndrome: Listeriosis in humans is not characterized by a unique set of symptoms since the course of the disease depends upon the state

Is crossing over important for the diversity of biological evolution? Sexual reproduction and recombination of linked genes (crossing over) are, with mutations, the main instru