Role of mesoderm and ectoderm in limb morphogenesis, Biology

Role of Mesoderm and Ectoderm in Limb Morphogenesis

A series of very interesting experiments on wing and leg buds of chick embryos have clarified the respective roles of mesoderm and ectoderm and interactions between them in limb development in vertebrates. Many of these experiments have involved separating the two components of early and later embryonic stages of the same or different limb types or even species and studying the development after recombining them with each other or with cells from non-limb regions in various ways. It is established that the presumptive limb mesoderm which is localized very early in the presumptive limb area is essential for Sib development. This is demonstrated by the following experiments:

1) When limb mesoderm is removed from under the ectoderm of limb area or replaced by mesoderm from some non-limb region, no limb forms.

2) The type of limb (wing or leg) that develops is determined by the mesoderm of limb site. Thus, when leg bud mesoderm is combined with wing bud ectoderm a leg is formed and vice versa. It means the mesoderm of each limb field is already determined as to what limb type it will form and determination is species specific.

3) When wing mesoderm is grafted under the ectoderm at a non-wing site in early embryo, a wing is formed at that site.

4) When limb bud ectoderm is grafted at a non-limb site, no limb is formed, but if limb bud ectoderm is replaced by non-limb ectoderm on the limb mesoderm. A normal limb forms. The ectoderm of any region up to a certain stage chick embryo (and also amphibians) is able to participate in limb development if associated with limb mesoderm.

Posted Date: 1/29/2013 6:06:01 AM | Location : United States







Related Discussions:- Role of mesoderm and ectoderm in limb morphogenesis, Assignment Help, Ask Question on Role of mesoderm and ectoderm in limb morphogenesis, Get Answer, Expert's Help, Role of mesoderm and ectoderm in limb morphogenesis Discussions

Write discussion on Role of mesoderm and ectoderm in limb morphogenesis
Your posts are moderated
Related Questions

Define Primary motor cortex corticospinal interneuron A Primary motor cortex (M1) corticospinal interneuron A that produces action potentials during movements of the big toe of

Q. Major objectives of diarrhoea? The major objectives in the management of diarrhoea include: 1. Fluid and electrolyte replacement 2. Removal of cause (especially if inf

Describe tranposition of great arteries with intact ventricular septum? Transposition of great arteries with intact ventricular septum (or small VSD): There is usually inadequa

1. Andalusian chickens may be either black, white, or gray. The gene for black is not dominant over the gene for white, nor is the gene for white dominant over the gene for black.

Compilations- Non-assurance Engagements Within a compilation engagement, such the accountant is engaged to need accounting expertise that opposed to auditing expertise to brin

What is produced at the end of the cell cycle? how do they compare to each other and to the parent cell? What happens to the parent cell?

Functional properties of proteins These are those physico-chemical properties that enable the proteins to contribute to the desirable characteristics of the food Potential f

Name some Drugs to prvent tuberculosis Pyrazinamide can cause morbilliform rash, arthralgias and asymptomatic hyperuricemia, and blocks the hypouricemic action of allopurinol (

a) Donald is a 50 year old male with a long history of bipolar disorder. He has been hospitalized three times in the last 8 months for manic episodes. He was just admitted to your