Regulation of Testicular
Activity The production of spermatozoa is under the influence of pituitary hormones and of androgens derived from the testis. The testicular tissue involute in the experimental animals deprived of pituitary hormones. FSH is required for the differentiation of spermatogonium into spermatozoa and LH (also known as interstitial cells stimulating hormone (ICSH) in males) to stimulate the Leydig cells for the production of androgens.
The increased levels of androgens in the blood suppress the synthesis and secretion of gonadotropins in the pituitary.You have studied earlier that the time required for the spermatogonia to differentiate into spermatozoa is a biologic constant, varying with the species and strain, which cannot be altered by hormones and other factors. On the other hand, the number of spermatozoa produced is dependent upon pituitary gonadotropins, androgens, nutritional factors. Temperature, light etc.