Reduction in left ventricular, Biology

Q. Reduction in left ventricular?

Vasodilators improve stroke volume, and reduce degree of regurgitation. This results from decrease in systemic vascular resistance and leads to reduction in left ventricular end diastolic volume, after load, wall stress and LV mass. They also preserve LV systolic function. Hydralazine and nefedipine when given at appropriate doses decrease left ventricular size and improve LV function. The dose should be titrated to bring down systolic blood pressure as much as possible without getting side effects. Less consistent results were obtained with ACE inhibitors and increased plasma renin activity is not an issue in these patients. Vasodilators may be given in any patient with severe AR with LV dysfunction and symptoms of heart failure when patient is a poor candidate for surgery. They may also be given to a patient with severe AR and LV dysfunction with or without symptoms to improve hemodynamic profile before surgery. They are also indicated in a patient with severe AR and normal LV function. Here they delay the onset of LV dysfunction, symptom onset and postpone the time for AVR and also improve operative outcomes. In this situation there is no proven role of any other medication. Vasodilators should not be used as a substitute for aortic valve replacement in a patient with severe AR who needs surgery either due to LV dysfunction or symptoms. They are also not indicated in patients with mild AR and normal sized left ventricle with good LV function. Following AVR, ACE inhibitors may be better choice in patients with persistent myocardial systolic dysfunction.

Posted Date: 5/28/2013 6:17:09 AM | Location : United States

Related Discussions:- Reduction in left ventricular, Assignment Help, Ask Question on Reduction in left ventricular, Get Answer, Expert's Help, Reduction in left ventricular Discussions

Write discussion on Reduction in left ventricular
Your posts are moderated
Related Questions
Q. Do all molecules of DNA have the same amounts of nitrogenous bases? Number and sequence of nitrogenous bases in DNA molecule are key elements in variations which are found i

There has not been rain for several months. A biologist is driving down the highway and notices that a large number of corn fields have corn that is wilted and short. She wonders i

What is the main evolutionary novelty presented by annelids? The main evolutionary novelty shown by the beings of the phylum Annelida is the coelom, the internal body cavity to

What are the Sources of Vitamin K? As mentioned above, in plants, the only important molecular 'form of vitamin K is phylloquinone. Phylloquinone is distributed ubiquitously th

How does the sodium-potassium pump present in the cell membrane work? What is the importance of this protein for the cell? The sodium-potassium pump is the transport protein th

What is the structure of the adult fern within which cells undergoing meiosis can be found? In these plants meiosis takes place within structures known as sorus (plural, sori),

Ecological Pyramids - Ecosystem The ancient Egyptians constructed elaborate tombs called pyramids. The base of the pyramid is broad and it supports the upper levels of the str

Pancreas Insulin (β cells) Promotes glucose entry in many cells, and in this way controls carbohydrate metabolism. Glucagon (α cells) Increases synthesis and release of

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4