Quaternary structure of protein, Biology

Quaternary Structure (4o Structure).

  • Globular in structure.
  • When two or more than two molecules of protein of tertiary structure are connected to each other through various bonds then this structure is called quaternary structure.
  • Most stable protein.
  • Haemoglobin has 4 polypeptide chains (2 a chains & 2 b chains).
  • Insulin consists of 2 polypeptide chains (1 a chain & 1 b chain).
  • A chain of insulin consists of 21 amino acids and b chain insulin consists 30 amino acids.
  • Total numbers of 51 amino acids are present in insulin
  • Molecular structure of insulin described by F. Sanger (He got 1st time Nobel Prize)
  • He got 2nd time Nobel Prize for preparing chromosomal maps.

1328_quaternary structure.png

  • Quaternary structure was first studied in case of haemoglobin by Kendrew and Perutz (1963).
Posted Date: 10/9/2012 5:54:21 AM | Location : United States







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