Primary tubercle, Biology

Primary  Tubercle  (Ghon Tubercle):

When  an  individual with  no  previous exposure  to  tuberclosis inhale a sufficient number of  tubercle bacilli into the alveoli, tuberculosis infection occurs. Inflammation occurs within the parenchyma of  the  lungs. Body  counteracts  the infection with  the natural  body defenses. Lymph  nodes in  the  hilar region  of the  lung become  enlarged as  they  filter drainage  form  the  infected site. The inflammatroy process and cellular reaction produce a small, firm white  nodule called  the  primary tubercle.

Calcifid Nodule  or Chon Tubercle:

The center of the primary tubercles contains tubercle bacilli. Cells gather around the center, and usually the outer portion becomes fibrosed. As blood vessels get compressed interfering with nutrition of  the tubercle, necrosis occurs at the center.


The area becomes walled off by fibrotic tissue around the outside, and the center gradually becomes soft and cheesy in consistency. This process is known as caseation necrosis. This material may become calcified (Ghon tubercle). Most people who are exposed  to tuberculosis and develop infection do not have active tuberculosis. X-ray shows the calcified nodule. The hilar lymph nodes and a Ghon tubercle seen is X-ray is referred as the primary complex. Person who have primary complex will show positive result inobatin  test. However a nurse needs to explain to the clients that a positive tuberculin test does not mean that helshe has tuberculosis. Body's reaction to  the organism. A person who has been unless with tubercle bacilli harbours the organism for the remainder of he person's  life unless he or she has received prophylactic isonizid. When a person is under physical or emotional stress, the bacilli lying dormant in the lungs become active. 

Posted Date: 10/27/2012 8:19:49 AM | Location : United States







Related Discussions:- Primary tubercle, Assignment Help, Ask Question on Primary tubercle, Get Answer, Expert's Help, Primary tubercle Discussions

Write discussion on Primary tubercle
Your posts are moderated
Related Questions
Define the Toxicity of Vitamin K? Vitamin K, does not produce any toxic effects in doses (10-20 mg) normally used for the treatment or subjects suffering from disorders of liv

Disposal : You must always sterilize cultures and contaminated instruments and glassware before disposing them of or before washing-up. Usually, you can do this by autoclaving or

Q. What is Phytates? Phytates are widely distributed in seeds of vegetables, fruits and grains. Unrefined cereals and millets are the richest sources of phytates. Refined or

Explain the Diet Counseling for a successful weight reduction programme? As discussed above diet counseling is a very important aspect of a successful weight reduction programm

When coal is carbonized coke is formed along with coal gas.                             1300 0 C          Coal                                  coke + coal gas

Dietary Management It must be evident to you that majority of the tuberculosis patients are emancipated and malnourished. Proper dietary management it during and  after the inf

Explain about the Vacuum Evaporators? It is common to construct various vacuumised vessels in series that is why the product moves from one vacuum chamber to the next and thus

Q. Understanding Behaviour of diabetic patients? Beliefs  Each of us has a set of beliefs that were learned by us when we were young. These include religious beliefs and

Explain the Food Irradiation - method of food preservation? Food irradiation is another sterilizing technique in which the foods are bombarded by high-energy rays called gamma

CRANIAL NERVES 12 pairs. Total weight 12 gms. Upto amphibian 10 pairs cranial nerves are present. 1, 2, 8, - sensory. 3, 4, 6, 11, 12, motor. 5, 7, 9, 10 - mixed. 3