Poly-functional enzymes, Biology

Bi-and Poly-Functional Enzymes

These enzymes are generated by genes obtained by fusion of the coding regions of two or more genes encoding various enzymes. In simple words, the strategy for generation of such enzymes is as follows. Consider gene a produces enzyme A and gene b create enzyme B, and for some reason it is desirable to bring the two enzyme activities together. The stop codon, e.g. TAG, of gene is removed, and that changed gene a is then connected with the initiation codon or TAG of gene b. It required, a linker sequence encoding 2-10 amino acids can be started between the genes b and a. It is required that the fusion of the two genes does not modify the reading frame of gene b, i.e. the two genes are refused in the general reading frame. The fused gene will give a single polypeptide which can possess/exhibit the activities of both the enzymes B and A.

 

 

 

Posted Date: 10/2/2012 1:23:40 AM | Location : United States







Related Discussions:- Poly-functional enzymes, Assignment Help, Ask Question on Poly-functional enzymes, Get Answer, Expert's Help, Poly-functional enzymes Discussions

Write discussion on Poly-functional enzymes
Your posts are moderated
Related Questions
Explain the Penicillium - Fungi? Classification Kingdom - Mycetae Division - Amastigomycota Class - Ascomycetes Subclass - Plectomycetidae Order - Eurotiales

Motion Sickness  The pathogenesis of motion sickness is poorly under- stood. The prescription cholinergic blocker scopolamine in a patch or oral formulation can decrease sympto

What are trophic levels? How many trophic levels can a food chain have? The Trophic levels correspond to positions on a food chain. thus producers always belong to the first tr

Describe the tailored to the individual patient? Patent ductus arteriosus (PDA) interruption (surgical or transcatheter intervention): It is a curative procedure. Atrial

Explain the Primary and Secondary air Pollutants a. Primary pollutants -emitted directly  Particulate matter ( Sulfur dioxide (SO 2 ) Nitrogen dioxide (NO 2 )

Explain brifly what is Genetic Engineering ? Genetic Engineering : Engineering techniques have been used in agriculture and horticulture for centuries. Certain plants or ani

Various cases  are  now  known  where  variant  tissues  splice  the  main  RNA transcript of a single gene by instead pathways, where the exons which are lost and those which are

In unilocular ovary with a single ovule tje placentation is??

If a diploid sperm fertilized a haploid egg, what would the result be? a.Haploid (n) b.Diploid (2n) c.A mixture of diploid (2n) and haploid (n) d.Triploid (3n)

Cytology: The study of form or culture including the behavior of nucleus and other organelles is called cytology. Cytology means "the study of cells". Cytology is the branch of lif