Pathophysiology of bronchial asthma, Biology

Pathophysiology

Asthma result from several physiological alterations, including altered immunologic response, increased airways resistance, increased lung-compliance, impaired mucociliary function. Asthma resulting from the antigen-antibody reaction in which chemical mediators such as histamine, eosinophilic factor etc. caused constriction of smooth muscles of both the large and small airways resulting in bronchospasm, increased capillary permeability resulting in mucosal oedema and increased mucus production.

Bronchospams causes increased airway resistance and obstruction to air flow in and out of lungs. The lung become hyperinflated resulting in increased lung compliance. The increased mucus production can cause formation of mucus plugged which can further block the airway. Impaired mucocilliary function, hypertrophy of mucus-secreting glands, thickened mucus and slowed ciliary movement are common findings in persons with asthma. During an attack, increased mucus production combined with slowed clearance of mucus due to decreased ciliary movement results in increased water loss from mucus. Mucus becomes viscous, forming a mucus plug which may block airways.

Increased airway resistance and hyperinflation can increase the work of respiratory muscles resulting in muscle fatigue and exhaustion. Resulting hypoventilation in severe cases lead to respiratory acidosis, and even death.

Posted Date: 11/5/2012 12:25:26 AM | Location : United States







Related Discussions:- Pathophysiology of bronchial asthma, Assignment Help, Ask Question on Pathophysiology of bronchial asthma, Get Answer, Expert's Help, Pathophysiology of bronchial asthma Discussions

Write discussion on Pathophysiology of bronchial asthma
Your posts are moderated
Related Questions
Define respiration in animals

Cattle and buffalo diseases Rinderpest: Rinderpest is the most destructive of the virus diseases of cloven-footed animals, viz. cattle, buffaloes, sheep, goats, pigs and wil

Explain the Heat Fixation Method? This is the usual method. Here, bacteria is fixed by gentle heating of air-dried bacterial film, which results in coagulation of bacterial pro

Anterior superior alveolar nerve It is a branch of infraorbital nerve which arises within the infraorbital canal. It gives a nasal branch which passes into nasal cavity to supp

Define features of Fusarium - Identification of Fungi and Yeasts? Identifying features of Fusarium: 1. Wooly, white fuzzy colonies changing colour to pink, purple or yellow.

Jackson Coleman and Fischer Theory Jackson Coleman Theory: During accommodation the ciliary muscle contraction causes an anterior thrust of the vitreous. This vitreous thrust p

Q. Since among the 64 codons of mRNA 61 codify amino acids that form polypeptide chains what are the functions of the three remaining codons? Since there are 20 amino acids and

What is Meiosis ? Meiosis starts with a diploid cell and forms four haploid, or 1n, (or "n") germ cells. These n germ cells fuse during fertilization with another germ cell to

Pyramid of Numbers - Ecological Pyramids A graphic representation of the total number of individuals of different species belonging to each trophic level in an ecosystem is kn

RADIOGRAPHY You  have read  in GNM courses about radiographical examination. In this text the discussion will be on the following radiographical tests.   Chest Roentgenogram