Pathophysiology and assessment of purpura, Biology

Assignment Help:

Pathophysiology 

Normally the platelets are formed from megakaryocytes (stem cells) in the.  bone marrow. These cells mature, fragment and are released in  the blood stream. In idiopathic thrombocytopenic purpura  there  is rapid platelet  destruction beacuse of presence of platelet antibodies which results  in bleeding. There is no  failure to produce platelets as there are abundant platelet precursors (megakaryocytes)  in the bone marrow. 

Assessment 

The child may present with petechiae ecchymosis, bleeding of the gums and epistaxis. Bleeding in  the skin may be seen prominently over the legs. There may be hematemesis, malena, haematuria and haemarthrosis which indicate  internal haemorrhage. There may also be occasional low grade fever. Anaemia may be present  if there  is significant  blood loss. Diagnostic evaluation includes laboratory examination of blood which reveals platelet  count below  (40,000) 20,000/mm3 other platelet function tests  such as tourniquet test, bleeding time and clot retraction is abnormal. The white blood cell count and cloting time  is normal. 


Related Discussions:- Pathophysiology and assessment of purpura

Why all specialization occurred during this time period, There is a lot of ...

There is a lot of dataset and hypothese that attempt to explain why there was a Cambrian Explosion. Using all supporting ideas, explain and write a paragraph on why all this specia

Define classification of weight imbalance, Define Classification of Weight ...

Define Classification of Weight Imbalance? Obesity is defined as a condition with accumulation of excess body fat. Do you think that a measure of how much fat a person has in i

Plant physiology, application of apical dominace in horticulture and agricu...

application of apical dominace in horticulture and agriculture short notes

Evolutionary Biology-Genetic Drift, Imagine a population evolving by geneti...

Imagine a population evolving by genetic drift in which the frequency of allele K is 0.65. What is the probability that at some point in the future allele K will drift to a frequen

In which way bacteria and the archaea different, How are the bacteria and t...

How are the bacteria and the archaea different from all the other cellular microbes? -They have cell walls? -They can move? -They reproduce asexually? -They have no nucleus?

Digestion and feeding mechanism, state 5 notification and feeding habits in...

state 5 notification and feeding habits in some animals

What is the official name of pyruvic acid, Q. What is the official name of ...

Q. What is the official name of pyruvic acid? Pyruvic acid is named as 2-oxopropanoic acid it is thus a molecule made of three linearly bound carbons with one extremity forming

What are sori, What are sori? The word "sori" is the plural form of "so...

What are sori? The word "sori" is the plural form of "sorus". In ferns, a sorus (pl. sori) is a cluster of sporangia on the edge or underside of a fertile frond. In lots of spe

Temperate deciduous forests, Going south of taiga you would reach the tempe...

Going south of taiga you would reach the temperate regions of the planet. These regions experience moderate temperatures on average that change during four distinct seasons. They h

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd