Pathophysiology and assessment of patent ductus arteriosus, Biology

Pathophysiology 

If  the ductus arteriosus does not close after birth, the higher pressure in the aorta than in the pulmonary artery causes the blood to flow from the aorta, through the patent ductus into the pulmonary artery thus resulting in left to right shunt. This results in increased work load on the left side of  the heart, increased vascular pressure  in the pulmonary tree and increased blood flow in the ascending aorta. 

Assessment 

The clinical features depend upon the size of  the ductus and the amount of  shunting. The defect is discovered only on routine examination of  a classic "machinery murmur" which occurs during systole as well as diastole. 

The mild symptoms may include growth retardation, dyspnoea on exertion, palpitation, easy fatigability and recurrent  respiratory infection. Other clinical symptoms may include heart rate over 150/minute, gallop rhythm due to rapid filling of the ventricle, bounding pulses due to increased systolic pressure and wide pulse pressure. In severely affected cases congestive heart failure may  be present. 

Radiologic examination and electrocardiogram shows enlargement of  left ventricle and left atrium. The ascending aorta is dilated and there is increased pulmonary vascularity. Echocardiogram  is normal and the cardiac catheterization  if  necessary shows increased pressure in right ventricle and pulmonary artery and oxygenated blood in pulmonary artery.  

Posted Date: 10/26/2012 8:42:18 AM | Location : United States







Related Discussions:- Pathophysiology and assessment of patent ductus arteriosus, Assignment Help, Ask Question on Pathophysiology and assessment of patent ductus arteriosus, Get Answer, Expert's Help, Pathophysiology and assessment of patent ductus arteriosus Discussions

Write discussion on Pathophysiology and assessment of patent ductus arteriosus
Your posts are moderated
Related Questions
diagram of phyllum protozoa

Andalusian chickens may be either black, white, or gray. The gene for black is not dominant over the gene for white, nor is the gene for white dominant over the gene for black. Whe

PLACEN T A - Placenta is the intimate connection between the foehls and the uterine wall of the mother to exchange the materials. Placenta is a tempormy endocrine gland

Insulin Syringes Syringes for insulin are designed for standard U-100 insulin. 1 ml of insulin has 100 standard units of insulin. Syringe has markings in insulin units it helps

How is retaining wall works? A retaining wall together with the backfill the wall retains and the soil that supports the wall is a highly indeterminate system. The magnitudes o

Explain the molecular difference between fats and oils. How do the differences affect their physical properties?

Define Excretion of toxins and Act as precursors? Excretion of toxins: Glucuronic acid, a metabolite of glucose, combines with chemical and bacterial toxins and some normal met

Protein Synthesis with DNA The central dogma of modern biochemistry is totally based on the coded information holded within deoxyribonucleic acid (DNA). Double stranded DNA is

Chymotrypsin Chymotrypsin  is secreted in an inactive form  'chymotrypsinogen',  which  is activated by  trypsin. Chymotrypsin  is specific  for  peptide  bonds containing unc

Describe Assist Control Ventilation (ACV) The machine delivers a set tidal volume at the set rate; besides, each time the patient breathes on his own, a machine breath is init