Pathophysiology and assessment of patent ductus arteriosus, Biology

Pathophysiology 

If  the ductus arteriosus does not close after birth, the higher pressure in the aorta than in the pulmonary artery causes the blood to flow from the aorta, through the patent ductus into the pulmonary artery thus resulting in left to right shunt. This results in increased work load on the left side of  the heart, increased vascular pressure  in the pulmonary tree and increased blood flow in the ascending aorta. 

Assessment 

The clinical features depend upon the size of  the ductus and the amount of  shunting. The defect is discovered only on routine examination of  a classic "machinery murmur" which occurs during systole as well as diastole. 

The mild symptoms may include growth retardation, dyspnoea on exertion, palpitation, easy fatigability and recurrent  respiratory infection. Other clinical symptoms may include heart rate over 150/minute, gallop rhythm due to rapid filling of the ventricle, bounding pulses due to increased systolic pressure and wide pulse pressure. In severely affected cases congestive heart failure may  be present. 

Radiologic examination and electrocardiogram shows enlargement of  left ventricle and left atrium. The ascending aorta is dilated and there is increased pulmonary vascularity. Echocardiogram  is normal and the cardiac catheterization  if  necessary shows increased pressure in right ventricle and pulmonary artery and oxygenated blood in pulmonary artery.  

Posted Date: 10/26/2012 8:42:18 AM | Location : United States







Related Discussions:- Pathophysiology and assessment of patent ductus arteriosus, Assignment Help, Ask Question on Pathophysiology and assessment of patent ductus arteriosus, Get Answer, Expert's Help, Pathophysiology and assessment of patent ductus arteriosus Discussions

Write discussion on Pathophysiology and assessment of patent ductus arteriosus
Your posts are moderated
Related Questions
Polyenes: amphotericin b Amphotericin B products are the only polyenes currently available for systemic treatment of fungal infections.  Nystatin, another polyene, is only avai

Nutrient Elements of Plants Let us first find out the chemical composition of plants and see which element nature has selected to support their healthy growth. Only then we wi

Calcium antagonists are not recommended for the treatment of CHF because of their negative inotropic effects. However, second-generation dihydropyridine-type calcium antagonists su

Features of Phylum Porifera and Eumetazoa Table: Distinctive Features of Phylum Porifera and Eumetazoa The branch Eumetazoa, as we have seen above, consist of meta

Morphological changes Regressive changes -These changes include the gradual reduction and ultimate disappearance of all those larval structures or organs that become redundan

Differentiate between Total Fertility Rate (TFR) and Replacement Level (RL) Due to uncontrolled excessive hunting the population of tigers in a forest becomes Zero. Discuss the

The PRS kit is comprised of          -5 variously sized trephines and corresponding tubes according to material if it's silver or silver point          -A transmetal bur

The presence of advanced plaques of types IV and Va allows clinical symptoms to develop. Atherosclerosis is a biphasic disease; in the first stage, advanced plaques are generated b

Match each of the methods or vectors below to an appropriate form of gene therapy, assigning two methods or vectors to each form. Use each method or vector only once. Methods/v

Q. Which chemical elements are involved to form most of living biological matter? The chemical elements that form most of the molecules of living beings are carbon (C), oxygen