Nucleic acids, Biology

Deoxyribonucleic Acid (DNA) - polymer of nucleotides containing genetic information that codes for proteins
Nucleotide - a monomer of DNA consisting of a ribose/deoxyribose sugar, a phosphate group and one of four possible bases

  • There are two types
    • DNA (ribose sugar that is missing an O on C-2)
    • RNA
  • Nitrogenous Bases
    • Purines (double rings)

                         Adenine

                         Guanine

            o   Pyramidines

                       Cytosine

                       Thymine (only in DNA)

                       Uracil (only in RNA)

  • A chain of nucleotides is called a strand
  • The bond between phosphate group on one nucleotide and the hydroxyl group of another
    • Phosphodiester bond è condensation reaction
  • RNA coils into a single helix strand
  • DNA coils into a double helical strand
  • Strict base pairing
    • C-G with 3 H-bonds
    • A-T with 2 H-bonds
    • Purine - pyramidine
  • DNA
    • Strands are anti-parallel
    • Each strand ends with a sugar on one end and a phosphate group on the other

 

  • Other nucleotides
    • ATP - Adenosine triphosphate
    • FAD - flavin adenine dinucleotide
    • NAD+ - nicoamide adenine dinucleotide
    • NADP, FADP
    • CAMP - cyclic adenosine monophosphate

 

  • Can form hybrid DNA with closely related organisms

 

 

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Posted Date: 8/20/2012 4:58:36 PM | Location : United States







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